PTH2
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Official Full Name
Parathyroid Hormone 2 -
Overview
TIP39 is related to parathyroid hormone (PTH; MIM 168450) and PTH-related protein (PTHRP; MIM 168470) and is a ligand;for PTH receptor-2 (PTHR2; MIM 601469) (John et al., 2002 (PubMed 11861531)). -
Synonyms
PTH2;parathyroid hormone 2;TIP39;tuberoinfundibular peptide of 39 residues;tuberoinfundibular 39 residues;tuberoinfundibular 39 residue protein;TIPF39;TIP 39
Recombinant Proteins
- Zebrafish
- Mouse
- Rhesus macaque
- Human
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PTH2-11618Z | Recombinant Zebrafish PTH2 | Mammalian Cell | Zebrafish | His |
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| PTH2-13654M | Recombinant Mouse PTH2 Protein | Mammalian Cell | Mouse | His |
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| PTH2-3694R | Recombinant Rhesus monkey PTH2 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| PTH2-2705HCL | Recombinant Human PTH2 293 Cell Lysate | HEK293 | Human | Non |
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| PTH2-3512R | Recombinant Rhesus Macaque PTH2 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| PTH2-3512R-B | Recombinant Rhesus Macaque PTH2 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| Pth2-521M | Recombinant Mouse Pth2 Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| PTH2-7263M | Recombinant Mouse PTH2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PTH2-7263M-B | Recombinant Mouse PTH2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PTH2 involved in several pathways and played different roles in them. We selected most pathways PTH2 participated on our site, such as Class B/2 (Secretin family receptors),G alpha (s) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with PTH2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signal Transduction | ARAP2,CALCB,CCNT2A,QRFPR,METAP2,RAMP2,SEPT7,TRH,ACVR1C,OXGR1 |
| Signaling by GPCR | ARHGAP4,XK,CNR2,SCT,OPN4B,EDNRAB,RGS17,GNA13B,RAMP2,S1PR5B |
| Class B/2 (Secretin family receptors) | EMR1,RAMP3,ADM2A,CALCRL,GNB3A,ADM,CALCA,ADM2,EMR4,PTHLHA |
| GPCR downstream signaling | ADORA1,OPN1MW,NPFFR2,CHRM3,CCR9,APLNR,CXCL13,ABHD6B,ADM2,RHOAE |
| GPCR ligand binding | GPR132,UTS2,GCGB,CCR7,CCL35.2,S1PR3,TAS2R7,OXGR1A.3,EDNRAB,RGS1 |
| G alpha (s) signalling events | VIP2,ADM2A,CRHR2,NPSR1,INSL3,CALCA,RLN3,RAMP1,GCGB,PTH |
Protein Function
PTH2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by PTH2 itself. We selected most functions PTH2 had, and list some proteins which have the same functions with PTH2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
PTH2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTH2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PTH2.
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References
- Dimitrov, E; Usdin, TB; et al. Tuberoinfundibular Peptide of 39 Residues Modulates the Mouse Hypothalamic-Pituitary-Adrenal Axis Via Paraventricular Glutamatergic Neurons. JOURNAL OF COMPARATIVE NEUROLOGY 518:4375-4394(2010).
- Matsumoto, M; Kondo, S; et al. Parathyroid hormone 2 receptor is a functional marker of nociceptive myelinated fibers responsible for neuropathic pain. JOURNAL OF NEUROCHEMISTRY 112:521-530(2010).
