PSMA6
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Official Full Name
proteasome (prosome, macropain) subunit, alpha type, 6 -
Overview
The 20S proteasome is the major proteolytic enzyme complex involved in intracellular protein degradation. It consists of four stacked rings, each with 7 distinct subunits. The two outer layers are identical rings composed of alpha subunits (called PSMAs), -
Synonyms
PSMA6;proteasome (prosome, macropain) subunit, alpha type, 6;proteasome subunit alpha type-6;IOTA;MGC2333;MGC22756;MGC23846;p27K;PROS27;PROS-27;macropain iota chain;prosomal P27K protein;proteasome iota chain;macropain subunit iota;27 kDa pr
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- Chicken
- E.coli
- Mammalian Cell
- Human
- HEK293
- HEK293T
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
PSMA6 involved in several pathways and played different roles in them. We selected most pathways PSMA6 participated on our site, such as Proteasome, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSMA6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Proteasome | PSMD4A,PSMA6A,PSMB9A,PSMD2,PSMB3,PSMC1B,PSMC3,IFNG1-2,PSMB5,PSMD13 |
Protein Function
PSMA6 has several biochemical functions, for example, NF-kappaB binding,RNA binding,endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PSMA6 itself. We selected most functions PSMA6 had, and list some proteins which have the same functions with PSMA6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | TMEM171,NGF,WBP11,EDAR,COL3A1,IL12A,NPM2,GUCY1B3,MTMR6,STAP2 |
| threonine-type endopeptidase activity | PSMB9B,PSMA2,PSMA3,PSMB10,PSMB8F,PSMA6B,PSMB9A,PSMB1,PSMB4,PSMA8 |
| endopeptidase activity | PSMA8,PSMB1,CTSH,KLK1B8,NCSTN,MMP1,ECE1,PSMB11,FURIN,PSMB10 |
| NF-kappaB binding | MTDH,ANXA4,RNF25,HIF1AN,EP300,NFKBID,FOXP3,RELA,FAF1,ANKRD42 |
| RNA binding | EWSR1,DZIP3,ADAD2,ADAD1,RPLP0,RBM5,NOL9,RBM12B2,RPLP2,SNRPF |
Interacting Protein
PSMA6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSMA6 here. Most of them are supplied by our site. Hope this information will be useful for your research of PSMA6.
PSMA3;PSMA7;PSMA1
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