PSMA3
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Official Full Name
proteasome (prosome, macropain) subunit, alpha type, 3 -
Overview
The 20S proteasome is the major proteolytic enzyme complex involved in intracellular protein degradation. It consists of four stacked rings, each with 7 distinct subunits. The two outer layers are identical rings composed of alpha subunits (called PSMAs), -
Synonyms
PSMA3;proteasome (prosome, macropain) subunit, alpha type, 3;proteasome subunit alpha type-3;HC8;macropain subunit C8;proteasome subunit C8;proteasome component C8;multicatalytic endopeptidase complex subunit C8;PSC3;MGC12306;MGC32631
Recombinant Proteins
- Human
- S.aureus
- Mouse
- Chicken
- Zebrafish
- Rhesus macaque
- Rat
- Staphylococcus aureus
- E.coli
- S. aureus
- Human
- Mammalian Cell
- HEK293
- E. coli
- HEK293T
- GST
- Non
- His
- Myc&DDK
- His&Fc&Avi
Involved Pathway
PSMA3 involved in several pathways and played different roles in them. We selected most pathways PSMA3 participated on our site, such as Proteasome, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSMA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Proteasome | PSMB6,PSMD12,PSMF1,PSMB9A,PSMD3,PSMB8F,PSMC3,PSME4B,PSMC1,PSMD6 |
Protein Function
PSMA3 has several biochemical functions, for example, endopeptidase activity,protein binding,threonine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PSMA3 itself. We selected most functions PSMA3 had, and list some proteins which have the same functions with PSMA3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ZNF302,SNAP29,TEKT5,NPEPL1,KLHL7,LARP4,PAX5,CBR2,DDX23,PI4KB |
| endopeptidase activity | NAPSA,KLK1B11,PSMA1,REN2,ACE2,KLK1B5,KLK1B3,PSMB7,PSMB1,FAP |
| threonine-type endopeptidase activity | PSMB9B,PSMB1,TASP1,PSMA6,PSMA8,PSMB7,PSMA1,PSMA5,PSMA7,PSMB10 |
Interacting Protein
PSMA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSMA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PSMA3.
PSMA1;PSMA7;PSMA6;PSMA4
Resources
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References
- Livinskaya, VA; Ivanov, VA; et al. Polyclonal Antibodies Against Human Proteasome Subunits PSMA3, PSMA5, and PSMB5. HYBRIDOMA 31:272-278(2012).
- Livinskaya, VA; Barlev, NA; et al. Immunoaffinity purification of the functional 20S proteasome from human cells via transient overexpression of specific proteasome subunits. PROTEIN EXPRESSION AND PURIFICATION 97:37-43(2014).
