PRPSAP1
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Official Full Name
phosphoribosyl pyrophosphate synthetase-associated protein 1 -
Overview
Phosphoribosyl pyrophosphate synthetase-associated protein 1 is an enzyme that in humans is encoded by the PRPSAP1 gene. -
Synonyms
PRPSAP1;phosphoribosyl pyrophosphate synthetase-associated protein 1;phosphoribosyl pyrophosphate synthase-associated protein 1;PAP39;39 kDa phosphoribosypyrophosphate synthase associated protein;39 kDa phosphoribosypyrophosphate synthase-associated protein;KPRA_HUMAN;Phosphoribosyl pyrophosphate synthase associated protein 1;Phosphoribosyl pyrophosphate synthetase associated protein 1;PRPP synthase associated protein 1;PRPP synthase-associated protein 1
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- Mammalian cells
- HEK293T
- GST
- His
- Non
- His&Fc&Avi
- Flag
- Myc&DDK
Involved Pathway
PRPSAP1 involved in several pathways and played different roles in them. We selected most pathways PRPSAP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PRPSAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PRPSAP1 has several biochemical functions, for example, enzyme inhibitor activity,kinase binding,magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PRPSAP1 itself. We selected most functions PRPSAP1 had, and list some proteins which have the same functions with PRPSAP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | FUNDC1,PRLR,COPS7A,HEY1,HDHD2,IQUB,KEL,SAMD4A,POLE4,MT1H |
| magnesium ion binding | TDP2,PDXP,RPS6KA3A,ATP11A,TSSK3,SIK3,ENO2,NLK,NUDT18,RNASEH1 |
| ribose phosphate diphosphokinase activity | PRPS2,PRPS1L1,PRPS1A,PRPS1B,PRPS1 |
| enzyme inhibitor activity | TAE1,OAZ1A,OAZ2A,FRY,ARRB1,UGT1A9,NOTCH1,ATPIF1A,CSN2,WFIKKN1 |
| kinase binding | JAKMIP2,BARD1,LDHB,CTNNB1,CEBPA,SNAI1,TAX1BP1,NTRK1,STUB1,CAB39 |
Interacting Protein
PRPSAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRPSAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRPSAP1.
PRPS1;PRPS2;NUAK1;PTP4A3;PRKRA;CD2BP2;PSPH;ILK;TMBIM4;TNIK;TRAF6
Resources
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References
- Kian, IA; Etingof, RN; et al. Purine biosynthesis de novo in bovine retina: Purification and characterization of amidophosphoribosyl transferase and phosphoribosyl pyrophosphate synthetase. BIOCHEMISTRY-MOSCOW 64:648-651(1999).
- Hernando, Y; Carter, AT; et al. Genetic analysis and enzyme activity suggest the existence of more than one minimal functional unit capable of synthesizing phosphoribosyl pyrophosphate in Saccharomyces cerevisiae. JOURNAL OF BIOLOGICAL CHEMISTRY 274:12480-12487(1999).
