PRPS1L1
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Official Full Name
phosphoribosyl pyrophosphate synthetase 1-like 1 -
Overview
This intronless gene is specifically expressed in the testis, and encodes a protein that is highly homologous to the two subunits of phosphoribosylpyrophosphate synthetase encoded by human X-linked genes, PRPS1 and PRPS2. These enzymes convert pyrimidine, purine or pyridine bases to the corresponding ribonucleoside monophosphates. In vitro transcription/translation and site-directed mutagenesis studies indicate that translation of this mRNA initiates exclusively at a non-AUG (ACG) codon. -
Synonyms
PRPS1L1;phosphoribosyl pyrophosphate synthetase 1-like 1;PRPSL;ribose-phosphate pyrophosphokinase 3;PRPS3;Phosphoribosyl pyrophosphate synthetase 1 like 1;Phosphoribosyl pyrophosphate synthetase III;Phosphoribosylpyrophosphate synthetase 1-like 1;Phosphoribosylpyrophosphate synthetase 3;PRPS1;PRPS1 like 1;PRS III;PRSIII;Ribose phosphate pyrophosphokinase 3;Ribose phosphate pyrophosphokinase III;Ribose-phosphate pyrophosphokinase;PRPS1-like 1;OTTHUMP00000202305;ribose-phosphate pyrophosphokinase III;phosphoribosyl pyrophosphate synthase III;phosphoribosyl pyrophosphate synthase 1-like 1;phosphoribosylpyrophosphate synthetase subunit III;ribose-;PRS-III
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PRPS1L1-1983H | Recombinant Human PRPS1L1, GST-tagged | E.coli | Human | GST | 1-318aa | |
| PRPS1L1-3722H | Recombinant Human PRPS1L1 protein, His-tagged | E.coli | Human | His | 1-318 aa | |
| PRPS1L1-504HCL | Recombinant Human PRPS1L1 lysate | HEK293 | Human | Non |
|
Involved Pathway
PRPS1L1 involved in several pathways and played different roles in them. We selected most pathways PRPS1L1 participated on our site, such as Pentose phosphate pathway,Purine metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRPS1L1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Pentose phosphate pathway | H6PD,RBKS,PGM1,DERA,FBP1,ALDOA,PRPS1B,PGM2,PGD,PRPS1A |
| Carbon metabolism | GPIB,G6PD,ACSS2,SDHC,PKMB,ACAT1,ALDOB,PSAT1,PKM2,ACSS2L |
| Metabolic pathways | HPDB,PTGIS,IL4I1,PLCZ1,CYP2C8,PFKL,CKMT2B,GFPT1,MVD,B4GALT6 |
| Purine metabolism | POLR2GL,ENTPD4,POLE4,PFAS,APRT,ENTPD3,FHIT,GMPR,POLR2D,GUCY1B3 |
| Biosynthesis of amino acids | TKTL2,PC,SHMT2,IDH2,PYCRL,GLULA,MAT2AL,PGAM1A,GPT,ENO2 |
Protein Function
PRPS1L1 has several biochemical functions, for example, ATP binding,kinase activity,magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PRPS1L1 itself. We selected most functions PRPS1L1 had, and list some proteins which have the same functions with PRPS1L1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| kinase activity | PRKAR2AA,STK30,KITB,SRPK1B,PRPS1,CDK5R1,MOB1BA,NEK5,HIPK2,DCLK2 |
| ATP binding | UBE2U,CLK4,TRIP13,UBE2F,ACSS1,Ckmm,P2RX3A,AAK1,HKDC1,KIF4A |
| ribose phosphate diphosphokinase activity | PRPS2,PRPS1,PRPSAP1,PRPS1A,PRPS1B |
| protein homodimerization activity | CAMK2A,AOC3,DDX1,RAG1,CBS,RPL7,LRRK2,CEP57,TYR,TDG |
| magnesium ion binding | CDC42BPA,S100P,NME1,PDXK,CDC42BPB,IDH1,NCS1,ALPI,NUDT18,PKMA |
Interacting Protein
PRPS1L1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRPS1L1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRPS1L1.
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