PRDM5
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Official Full Name
PR domain containing 5 -
Overview
The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. -
Synonyms
PRDM5;PR domain containing 5;PR domain zinc finger protein 5;PFM2;PR domain containing protein 5;PRDM 5;PRDM5 protein;PR domain-containing protein 5;BCS2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PRDM5-1937H | Recombinant Human PRDM5, GST-tagged | E.coli | Human | GST | 1-111aa | |
| PRDM5-13318M | Recombinant Mouse PRDM5 Protein | Mammalian Cells | Mouse | His |
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| PRDM5-451Z | Recombinant Zebrafish PRDM5 | Mammalian Cells | Zebrafish | His |
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| PRDM5-7068M | Recombinant Mouse PRDM5 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PRDM5-7068M-B | Recombinant Mouse PRDM5 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PRDM5 involved in several pathways and played different roles in them. We selected most pathways PRDM5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PRDM5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PRDM5 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,metal ion binding,methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRDM5 itself. We selected most functions PRDM5 had, and list some proteins which have the same functions with PRDM5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding | BCL11AA,BACH1,BATF3,HMGA2,NEUROG3,GCFC2,NACC2,PPARA,ATF3,ZBTB20 |
| sequence-specific DNA binding | SALL3B,PPARDB,FOXF2,NKX6.1,TFCP2,SPIC,TCF7L1A,NKX1.2LB,HOXA11B,SALL1 |
| metal ion binding | ZNF185,PXNA,ZDHHC8B,DAGLB,IRF2BPL,ZFP2,XGB,ZBTB1,SMPD3,REV3L |
| transcription regulatory region DNA binding | DDIT3,ASH2L,FOXA1,TBL1XR1,FOXA2,SALL1,SOX2,ATMIN,ZNF567,TCF7L1A |
| methyltransferase activity | PRDM12,KMT2A,PCMT,METTL5,DNMT3AB,PRDM13,PRDM15,RG9MTD3,METTL23,TRMT10B |
| protein binding | Anks6,SYNGR1,LACE1,ATOX1,JIP1,PIPOX,PLSCR1,RAB7,PARVG,MTAP1A |
| repressing transcription factor binding | NOC2L,TCF3,TBP,MAGEA2,CTBP1,SKI,HDAC5,SRI,CBX5,CTNNB1 |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | IFI16,MEIS1,CTCFL,MYPOP,KLF17,ETV6,FOSL1A,ELF1,IFI203,SMAD2 |
Interacting Protein
PRDM5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRDM5 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRDM5.
HDAC1;GFI1;EHMT2;TFAP4
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References
- Makiyama, Y; Kikuchi, T; et al. Clinical and Immunological Characterization of Paraneoplastic Retinopathy. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 54:5424-5431(2013).
- Petukhova, NV; Gasanova, TV; et al. Immunogenicity and Protective Efficacy of Candidate Universal Influenza A Nanovaccines Produced in Plants by Tobacco Mosaic Virus-based Vectors. CURRENT PHARMACEUTICAL DESIGN 19:5587-5600(2013).
