PRAM1
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Official Full Name
PML-RARA regulated adaptor molecule 1 -
Overview
The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha). -
Synonyms
PRAM1;PML-RARA regulated adaptor molecule 1;PML-RARA-regulated adapter molecule 1;PML RAR;PML RARA target gene encoding an Adaptor Molecule 1;PRAM;PML-RARA target gene encoding an Adaptor Molecule-1;PRAM-1;PML-RAR
Recombinant Proteins
- Human
- Mouse
- HEK293
- Mammalian Cell
- HEK293T
- Mamanlian cells
- Myc&DDK
- His
- Non
- His&Fc&Avi
- Flag
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PRAM1-12H | Recombinant Human PRAM1 protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| PRAM1-13293M | Recombinant Mouse PRAM1 Protein | Mammalian Cell | Mouse | His |
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| PRAM1-2898HCL | Recombinant Human PRAM1 293 Cell Lysate | HEK293 | Human | Non |
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| PRAM1-2835H | Recombinant Human PRAM1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Pram1-5095M | Recombinant Mouse Pram1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| PRAM1-7058M | Recombinant Mouse PRAM1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PRAM1-7058M-B | Recombinant Mouse PRAM1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| PRAM1-8365HFL | Recombinant Full Length Human PRAM1 protein, Flag-tagged | Mamanlian cells | Human | Flag | Full L. |
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Involved Pathway
PRAM1 involved in several pathways and played different roles in them. We selected most pathways PRAM1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PRAM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
PRAM1 has several biochemical functions, for example, lipid binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PRAM1 itself. We selected most functions PRAM1 had, and list some proteins which have the same functions with PRAM1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | LCE4A,IKBKG,ADAMTS5,AK8,MAPK6,APOO,RABAC1,SKA3,CHMP2B,HSPG2 |
| lipid binding | RASGRP2,STARD7,RUFY1,O3far1,Fert2,Ar,FABP7A,LIPF,SH3GL1,SH3GL3 |
Interacting Protein
PRAM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRAM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRAM1.
TRIM27;FXR2;CCDC57;KRT40;SKAP1;ABI2;RNF32
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