PPP6R3

  • Official Full Name

    protein phosphatase 6, regulatory subunit 3

  • Overview

    Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits;by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the;holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725);(Stefansson and Brautigan, 2006 (PubMed 16769727)).

  • Synonyms

    PPP6R3;protein phosphatase 6, regulatory subunit 3;C11orf23, chromosome 11 open reading frame 23 , SAPS domain family, member 3 , SAPS3;serine/threonine-protein phosphatase 6 regulatory subunit 3;DKFZp781E2374;DKFZp781E17107;DKFZp781O2362;FLJ11058;FLJ43065;KIAA1558;MGC125711;MGC125712;PP6R3;SAP190;SAPL;SAPLa;sporulation induced transcript 4 associated protein;C11orf23;Chromosome 11 open reading frame 23;PP6R3_HUMAN;Protein phosphatase 6 regulatory subunit 3;SAPS domain family member 3;SAPS domain family, member 3;Sporulation induced transcript 4 associated protein SAPL;Sporulation-induced transcript 4-associated protein SAPL;SAPS3

Recombinant Proteins

  • Zebrafish
  • Mouse
  • Chicken
  • Human
  • Mammalian Cell
  • HEK293
  • HEK293T
  • His
  • Non
  • Myc&DDK
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
PPP6R3-10082Z Recombinant Zebrafish PPP6R3 Mammalian Cell Zebrafish His
PPP6R3-13279M Recombinant Mouse PPP6R3 Protein Mammalian Cell Mouse His
PPP6R3-2850C Recombinant Chicken PPP6R3 Mammalian Cell Chicken His
PPP6R3-2066HCL Recombinant Human SAPS3 293 Cell Lysate HEK293 Human Non
Ppp6r3-5087M Recombinant Mouse Ppp6r3 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
PPP6R3-7048M Recombinant Mouse PPP6R3 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
PPP6R3-7048M-B Recombinant Mouse PPP6R3 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    PPP6R3 involved in several pathways and played different roles in them. We selected most pathways PPP6R3 participated on our site, such as Asparagine N-linked glycosylation,COPII (Coat Protein 2) Mediated Vesicle Transport,ER to Golgi Anterograde Transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP6R3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Transport to the Golgi and subsequent modification PPP6C,TRAPPC9,CNIH2,ANKRD28,NAPG,SCFD1,TRAPPC1,CNIH,SEC22A,TRAPPC10
    Asparagine N-linked glycosylation PREB,PPP6C,TRAPPC6B,TRAPPC4,CTSZ,SEC23A,TRAPPC3,SERPINA1L,TRAPPC6BL,MPDU1B
    Membrane Trafficking EXOC1,DNASE2,EXOC3,TRAPPC1,ANKRD28,TPD52,TFG,TRAPPC2L,DTNBP1B,CX30.3
    Post-translational protein modification GNE,GALNT5,DPH2,PPP6C,LMAN2,ADAMTS5,CNIH2,TMED10,ST6GALNAC1.2,DHPS
    Metabolism of proteins MIA3,CNIH3,MPDU1B,FKBP9,VBP1,MUC5AC,TOMM40,ST3GAL3A,EIF5A2,TIMM9
    Vesicle-mediated transport DTNBP1B,COPZ1,ARCN1,CX30.3,GJB5,CPD,TRAPPC6BL,PICALMB,TBC1D8B,SCGB3A2
    COPII (Coat Protein 2) Mediated Vesicle Transport CNIH3,CSNK1D,TFG,TMED2,TMED10,SCFD1,TRAPPC6BL,MCFD2,CNIH2,PREB
    ER to Golgi Anterograde Transport NSFA,NAPG,MCFD2,USO1,BET1,CTAGE5,YKT6,LMAN2L,CTSZ,NAPAA

    Protein Function

    PPP6R3 has several biochemical functions, for example, protein binding,protein phosphatase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP6R3 itself. We selected most functions PPP6R3 had, and list some proteins which have the same functions with PPP6R3. You can find most of the proteins on our site.

    Function Related Protein
    protein phosphatase binding DRD1,TRAF2,CSK,MET,ANAPC7,NEK2,CTNNB1,AP3B1,GNB2L1,LCK
    protein binding INPP5D,NUMBL,TJP2,SF3B3,UBASH3B,KLRG1,ZBTB6,NEDD8,FAM83A,METTL13

    Interacting Protein

    PPP6R3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP6R3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP6R3.

    PPP6C;ANKRD28;TERF2IP;NFKBIE;USP49;TNIP3;USP36;USP21;yscO;TINF2;mdm2_human_probe

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