PPP6R1
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Official Full Name
protein phosphatase 6, regulatory subunit 1 -
Overview
Protein phosphatase regulatory subunits, such as SAPS1, modulate the activity of protein phosphatase catalytic subunits;by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the;holoenzyme. SAPS1 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725);(Stefansson and Brautigan, 2006 (PubMed 16769727)). -
Synonyms
PPP6R1;protein phosphatase 6, regulatory subunit 1;KIAA1115 , SAPS domain family, member 1 , SAPS1;serine/threonine-protein phosphatase 6 regulatory subunit 1;SAP190;PP6R1;SAPS domain family, member 1;SAPS1;KIAA1115
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PPP6R1-13277M | Recombinant Mouse PPP6R1 Protein | Mammalian Cell | Mouse | His |
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| PPP6R1-2808H | Recombinant Human PPP6R1 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| PPP6R1-3278H | Recombinant Human PPP6R1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Ppp6r1-5086M | Recombinant Mouse Ppp6r1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| PPP6R1-7047M | Recombinant Mouse PPP6R1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PPP6R1-7047M-B | Recombinant Mouse PPP6R1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PPP6R1 involved in several pathways and played different roles in them. We selected most pathways PPP6R1 participated on our site, such as Asparagine N-linked glycosylation,COPII (Coat Protein 2) Mediated Vesicle Transport,ER to Golgi Anterograde Transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP6R1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Asparagine N-linked glycosylation | ST6GALNAC1.2,YKT6,SEC16B,NAPB,STT3A,ANKRD28,DDOST,CNIH3,NEU3,GNE |
| Metabolism of proteins | YKT6,ADAMTSL1,SERP1,KCNA3,GALNT5,EEF1D,NAPAB,FBXW5,PDIA6,GALNT6 |
| COPII (Coat Protein 2) Mediated Vesicle Transport | SCFD1,AREG,NSFB,SEC22C,CNIH2,PREB,MCFD2,TRAPPC2L,TFG,TMED10 |
| Post-translational protein modification | EIF5A2,SLC35A1,ARSH,ARSE,NAPAA,DPH1,MPDU1,NEU3,GALNTL5,PHC3 |
| Membrane Trafficking | NAPG,CNIH3,ANKRD28,BLOC1S3,TCEAL4,PUM1,COPZ1,TGOLN2,PICALM,GJA4 |
| ER to Golgi Anterograde Transport | TMED2,CTSZ,AREG,TRAPPC10,NAPG,ANKRD28,USO1,NAPB,CTAGE5,GORASP1 |
| Vesicle-mediated transport | TERFA,COPB1,SCGB3A2,NAPB,CX27.5,HYOU1,STAB2,GJA4,DNASE2,PLDN |
| Transport to the Golgi and subsequent modification | MIA3,YKT6,TRAPPC10,LMAN2L,TRAPPC6A,PPP6R3,SEC22A,MGAT4A,NAPB,SEC16B |
Protein Function
PPP6R1 has several biochemical functions, for example, protein phosphatase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP6R1 itself. We selected most functions PPP6R1 had, and list some proteins which have the same functions with PPP6R1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein phosphatase binding | CTNNB1,FGF19,ITGA1,ANAPC5,PIK3R1,GNB2L1,PPARG,VCAN,STAT3,DLG3 |
Interacting Protein
PPP6R1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP6R1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP6R1.
PPP6C;ANKRD28;TFRC;TUBB;TUBA1B;PRKDC;TIAL1;CRYZ;GTF3C1;TRAP1;BLMH;MYPN;Rpgrip1l;SPG20;ANKRD44;ANKRD52;GCN1L1;ARHGEF2;TUBB6;SPATA5L1
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