PPP4R4
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Official Full Name
protein phosphatase 4, regulatory subunit 4 -
Overview
The protein encoded by this gene is a HEAT-like repeat-containing protein. The HEAT repeat is a tandemly repeated, 37-47 amino acid long module occurring in a number of cytoplasmic proteins. Arrays of HEAT repeats form a rod-like helical structure and appear to function as protein-protein interaction surfaces. The repeat-containing region of this protein has some similarity to the constant regulatory domain of the protein phosphatase 2A PR65/A subunit. The function of this particular gene product has not been determined. Alternative splicing has been observed for this gene and two transcript variants encoding distinct isoforms have been identified. -
Synonyms
PPP4R4;protein phosphatase 4, regulatory subunit 4;KIAA1622;serine/threonine-protein phosphatase 4 regulatory subunit 4;PP4R4;HEAT-like repeat-containing protein
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PPP4R4-1926H | Recombinant Human PPP4R4, GST-tagged | E.coli | Human | GST | 1-98aa | |
| PPP4R4-245H | Recombinant Human PPP4R4 Protein, His-tagged | E.coli | Human | His |
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| PPP4R4-2909HCL | Recombinant Human PPP4R4 293 Cell Lysate | HEK293 | Human | Non |
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| PPP4R4-2910HCL | Recombinant Human PPP4R4 293 Cell Lysate | HEK293 | Human | Non |
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Involved Pathway
PPP4R4 involved in several pathways and played different roles in them. We selected most pathways PPP4R4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP4R4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
PPP4R4 has several biochemical functions, for example, protein binding,protein phosphatase regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP4R4 itself. We selected most functions PPP4R4 had, and list some proteins which have the same functions with PPP4R4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PPARA,CHN2,GTF2F2,MC5R,ADAMTS10,SRPK2,STK40,AGTR1A,ADRBK1,GRM1 |
| protein phosphatase regulator activity | PPP1R3CB,PPP1R3C,PPP1R3CA,SHOC2,PPP1R3B |
Interacting Protein
PPP4R4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP4R4 here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP4R4.
PPP4C;PARP2;HSPA5
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References
- Kitabatake, M; Soma, M; et al. JNK Regulatory Molecule G5PR Induces IgG Autoantibody-Producing Plasmablasts from Peritoneal B1a Cells. JOURNAL OF IMMUNOLOGY 194:1480-1488(2015).
- Lee, J; Lee, DH; et al. Leucine methylation of protein phosphatase PP4C at C-terminal is critical for its cellular functions. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 452:42-47(2014).
