PPP2R5E

  • Official Full Name

    protein phosphatase 2, regulatory subunit B, epsilon isoform

  • Overview

    The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an epsilon isoform of the regulatory subunit B56 subfamily.

  • Synonyms

    PPP2R5E;protein phosphatase 2, regulatory subunit B, epsilon isoform;protein phosphatase 2, regulatory subunit B (B56), epsilon isoform;serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform;2A5E_HUMAN;Epsilon isoform of regulatory subunit B56 protein phosphatase 2A;PP2A B subunit B epsilon;PP2A B subunit B epsilon isoform;PP2A B subunit B56 epsilon;PP2A B subunit B56 epsilon isoform;PP2A B subunit isoform B-epsilon;PP2A B subunit isoform B56-epsilon;PP2A B subunit isoform PR61-epsilon;PP2A B subunit isoform R5-epsilon;PP2A B subunit PR61 epsilon;PP2A B subunit PR61 epsilon isoform;PP2A B subunit R5 epsilon;PP2A B subunit R5 epsilon isoform;Protein phosphatase 2 regulatory subunit B (B56) epsilon isoform;Protein phosphatase 2 regulatory subunit B epsilon isoform;Regulatory subunit B of protein phosphatase 2 epsilon isoform;Serine/threonine protein phosphatase 2A 56 kDa regulatory subunit epsilon;OTTHUMP00000179057;OTTHUMP00000245210;PP2A, B subunit, B epsilon;PP2A, B subunit, R5 epsilon;PP2A, B subunit, B56 epsilon;PP2A, B subunit, PR61 epsilon;epsilon isoform of regulatory subunit B56, protein phosphatase 2A;serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, epsilon

Recombinant Proteins

  • Mouse
  • Rhesus macaque
  • Human
  • Mammalian Cell
  • HEK293
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
PPP2R5E-13265M Recombinant Mouse PPP2R5E Protein Mammalian Cell Mouse His
PPP2R5E-3575R Recombinant Rhesus monkey PPP2R5E Protein, His-tagged Mammalian Cell Rhesus macaque His
PPP2R5E-1405HCL Recombinant Human PPP2R5E cell lysate Human Non
PPP2R5E-3393R Recombinant Rhesus Macaque PPP2R5E Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
PPP2R5E-3393R-B Recombinant Rhesus Macaque PPP2R5E Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
PPP2R5E-7040M Recombinant Mouse PPP2R5E Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
PPP2R5E-7040M-B Recombinant Mouse PPP2R5E Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    PPP2R5E involved in several pathways and played different roles in them. We selected most pathways PPP2R5E participated on our site, such as mRNA surveillance pathway,Sphingolipid signaling pathway,Oocyte meiosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP2R5E were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Oocyte meiosis RBX1,SMC1A,CPEB1A,CALM4,CTH1,IGF1R,CCNE1,CDK1,CALM1B,CPEB1B
    mRNA surveillance pathway PPP2R5EA,MAGOH2,PCF11,BAT1,NXF3,SSU72,PELO,PPP2R2C,UPF1,PPP1CBL
    Adrenergic signaling in cardiomyocytes AGTR1,CACNG6A,TNNT2,CAMK2D,CACNA1SA,TPM4A,CACNA1DA,ATP1A2,AKT2,AKT1
    Dopaminergic synapse PPP2R3C,GNG8,PLCB2,PPP2R3A,GNAI3,GNG2,PPP2R2A,PPP2R5D,KIF5C,DRD2
    AMPK signaling pathway PFKP,EIF4EBP1,PFKFB1,CCNA1,CREB5,SREBF1,CPT1B,HMGCR,PFKFB2,RAB10
    Sphingolipid signaling pathway AKT1,TNF,TP53,CERS5,KRAS,ROCK2,DEGS1,PTEN,TRP53,ASAH1
    PIK-Akt signaling pathway LPAR6,Il2,LPAR3,FGF12,IGF1,ITGA2B,SGK1,PIK3CD,KITLG,FLT1

    Protein Function

    PPP2R5E has several biochemical functions, for example, protein binding,protein phosphatase type 2A regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP2R5E itself. We selected most functions PPP2R5E had, and list some proteins which have the same functions with PPP2R5E. You can find most of the proteins on our site.

    Function Related Protein
    protein phosphatase type 2A regulator activity PPP2R4,PPP2R2BB,PPP2R2C,IGBP1,PPP2R5CB,PPP2R1B,ENSA,EIF2AK2,PPP2R5EA,PPP2R1A
    protein binding GLI1,NKX3-1,ASL,SPRR1A,OIP5,GNAS,KIF23,HOXD12,GOLGA7,RP2

    Interacting Protein

    PPP2R5E has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP2R5E here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP2R5E.

    PPP2R1A;PPP2CA;PPP2R1B;RACGAP1;DZIP1;Soga1

    Resources

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