PPP1R3C
-
Official Full Name
protein phosphatase 1, regulatory subunit 3C -
Overview
This gene encodes a regulatory subunit of protein phosphatase-1 (PP1). PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities: neuronal, muscular, RNA splicing, protein synthesis, cell death, and glycogen metabolism, to name just a few. By interacting with different regulatory subunits, PP1 is directed to different parts of the cell, to different substrates, or to respond to extracellular signals. -
Synonyms
PPP1R3C;protein phosphatase 1, regulatory subunit 3C;PPP1R5, protein phosphatase 1, regulatory (inhibitor) subunit 3C;protein phosphatase 1 regulatory subunit 3C;Phosphatase 1;regulatory inhibitor subunit 5;protein targeting to glycogen;PTG;OTTHUMP00000020089;Phosphatase 1, regulatory inhibitor subunit 5;PP1 subunit R5;PPP1R5;PPR3C_HUMAN;Protein phosphatase 1 regulatory subunit 5;protein phosphatase 1, regulatory (inhibitor) subunit 3C;R5
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
PPP1R3C involved in several pathways and played different roles in them. We selected most pathways PPP1R3C participated on our site, such as Insulin signaling pathway,Insulin resistance, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP1R3C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Insulin resistance | PIK3R3B,OGT,NR1H2,PTPN1,AKT2,CREB1A,PTPN11A,PTPRFB,CREB3L3L,RPS6KB2 |
| Insulin signaling pathway | MAP2K2B,RAF1B,FASN,IRS4,G6PCA.1,SOCS1A,PRKACAB,GSK3B,PRKAA1,CBL |
Protein Function
PPP1R3C has several biochemical functions, for example, protein binding,protein phosphatase binding,protein phosphatase regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP1R3C itself. We selected most functions PPP1R3C had, and list some proteins which have the same functions with PPP1R3C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein phosphatase binding | AP3B1,STAT6,MAP3K5,DLG4,EGFR,VCP,HSF4,ROS1,CDKN1B,TP53 |
| protein binding | SUV420H2,ZDHHC17,AGXT2L2,POMGNT1,SF3B4,H2AFY,ATF5,POLDIP3,ADAM8,TINF2 |
| protein phosphatase regulator activity | SHOC2,PPP4R4,PPP1R3CA,PPP1R3B,PPP1R3CB |
| protein serine/threonine phosphatase activity | PPM1E,PPM1L,PPEF2,PPM1DA,CDC14B,TAB1,TIMM50,PPP3CA,MTMR4,LCK |
Interacting Protein
PPP1R3C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP1R3C here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP1R3C.
EPM2A;PPP1CB;SGTA;PPP1CA
Resources
Related Services
Related Products
References
