PPIH

  • Official Full Name

    peptidylprolyl isomerase H (cyclophilin H)

  • Overview

    The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome.

  • Synonyms

    PPIH;peptidylprolyl isomerase H (cyclophilin H);peptidyl prolyl isomerase H (cyclophilin H);peptidyl-prolyl cis-trans isomerase H;cyclophilin H;CYP 20;CYPH;MGC5016;peptidyl prolyl cis trans isomerase H;PPIase h;rotamase H;small nuclear ribonucleoprotein particle specific cyclophilin H;SnuCyp 20;U snRNP associated cyclophilin SunCyp 20;USA CYP;USA CyP SnuCyp 20;EC 5.2.1.8;Peptidylprolyl isomerase H;PPIH_HUMAN;RGD1564921;Small nuclear ribonucleoprotein particle-specific cyclophilin H;U snRNP associated cyclophilin SnuCyp 20;U-snRNP-associated cyclophilin SnuCyp-20;USA-CYP;USACYP;UsnRNP associated cyclophilin SnuCyp20;USA-CyP SnuCyp-20;U-snRNP-associated cyclophilin SunCyp-20;CYP-20;SnuCyp-20

Recombinant Proteins

  • Human
  • Zebrafish
  • Rhesus macaque
  • Chicken
  • Mouse
  • E.coli
  • Mammalian Cell
  • HEK293
  • HEK293T
  • Non
  • His
  • HIS
  • T7
  • His&Fc&Avi
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
PPIH-111H Recombinant Human Peptidylprolyl Isomerase H E.coli Human Non
PPIH-11421Z Recombinant Zebrafish PPIH Mammalian Cell Zebrafish His
PPIH-181H Recombinant Human PPIH Protein, HIS-tagged E.coli Human HIS
PPIH-1980Z Recombinant Zebrafish PPIH Mammalian Cell Zebrafish His
PPIH-219H Recombinant Human PPIH protein, T7-tagged E.coli Human T7
PPIH-30106TH Recombinant Human PPIH E.coli Human Non Full L.
PPIH-30685TH Recombinant Human PPIH, T7 -tagged E.coli Human T7 Full L.
PPIH-3549R Recombinant Rhesus monkey PPIH Protein, His-tagged Mammalian Cell Rhesus macaque His
PPIH-5245C Recombinant Chicken PPIH Mammalian Cell Chicken His
PPIH-2969HCL Recombinant Human PPIH 293 Cell Lysate HEK293 Human Non
PPIH-3367R Recombinant Rhesus Macaque PPIH Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
PPIH-3367R-B Recombinant Rhesus Macaque PPIH Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
PPIH-4397H Recombinant Human PPIH Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
Ppih-5043M Recombinant Mouse Ppih Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
PPIH-5544H Recombinant Human PPIH Protein (Met1-Met177), N-His tagged E.coli Human His Met1-Met177

    Involved Pathway

    PPIH involved in several pathways and played different roles in them. We selected most pathways PPIH participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPIH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Spliceosome SART1,DDX46,HSP70L,RBMX,MAGOHB,SF3A3,HNRNPA1,MAGOH,HNRNPA3,PRPF31

    Protein Function

    PPIH has several biochemical functions, for example, cyclosporin A binding,peptidyl-prolyl cis-trans isomerase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPIH itself. We selected most functions PPIH had, and list some proteins which have the same functions with PPIH. You can find most of the proteins on our site.

    Function Related Protein
    cyclosporin A binding PPID,PPIF,PPIC,PPIE,PPIG
    peptidyl-prolyl cis-trans isomerase activity PPP2R4,FKBP3,PPIL3,CWC27,FKBP10,TTC9B,PPIF,FKBP6,PPIL4,PPIL1
    protein binding PICALM,DIEXF,HADHB,H2AFZ,MRE11A,ZBTB1,MATN3,C1orf189,NOL4,SLC22A3
    ribonucleoprotein complex binding SECISBP2,PRMT7,PITX2,PES,YBX2,SRP54,CD2BP2,PRPF31,TIMM50,UHMK1

    Interacting Protein

    PPIH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPIH here. Most of them are supplied by our site. Hope this information will be useful for your research of PPIH.

    PRPF4;N4BP2L2;VCAM1;USP4;SART3;Prpf8;TNIK;USP15;BAG2;PTBP3

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