PPIC
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Official Full Name
peptidylprolyl isomerase C (cyclophilin C) -
Overview
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase)) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. Similar to other PPIases, this protein can bind immunosuppressant cyclosporin A. -
Synonyms
PPIC;peptidylprolyl isomerase C (cyclophilin C);peptidyl-prolyl cis-trans isomerase C;CYPC;Cyclophilin C;Peptidyl prolyl cis trans isomerase C;PPIase C;Rotamase C;parvulin
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- GST
- His
- His&GST
- Non
- His&Trx
- His&Fc&Avi
- Myc&DDK
Involved Pathway
PPIC involved in several pathways and played different roles in them. We selected most pathways PPIC participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PPIC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PPIC has several biochemical functions, for example, cyclosporin A binding,peptidyl-prolyl cis-trans isomerase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPIC itself. We selected most functions PPIC had, and list some proteins which have the same functions with PPIC. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| peptidyl-prolyl cis-trans isomerase activity | PPIAA,PPIAL4C,FKBPL,PIN4,RANBP2,TTC9C,FKBP6,PPP2R4,PPIH,FKBP3 |
| cyclosporin A binding | PPIG,PPIH,PPIE,PPID,PPIF |
| protein binding | ATP1A2,CD8B,LNX2,PPP2R1B,HMGN2,CDC45,DLGAP4,FBXO27,KIF27,FBN1 |
Interacting Protein
PPIC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPIC here. Most of them are supplied by our site. Hope this information will be useful for your research of PPIC.
SGTA;BANP;UBAP1;UBQLN1;UBQLN1;ARSA;UBQLN4
Resources
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References
- Romero-Saavedra, F; Laverde, D; et al. Identification of Peptidoglycan-Associated Proteins as Vaccine Candidates for Enterococcal Infections. PLOS ONE 9:-(2014).
- Morales-Alvarez, ED; Rivera-Hoyos, CM; et al. Low-Scale Expression and Purification of an Active Putative Iduronate 2-Sulfate Sulfatase-Like Enzyme from Escherichia coli K12. JOURNAL OF MICROBIOLOGY 51:213-221(2013).
