PPFIBP1
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Official Full Name
PTPRF interacting protein, binding protein 1 (liprin beta 1) -
Overview
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported. -
Synonyms
PPFIBP1;PTPRF interacting protein, binding protein 1 (liprin beta 1);liprin-beta-1;hSGT2;hSgt2p;L2;SGT2;liprin-beta 1;liprin related protein;PTPRF-interacting protein-binding protein 1;protein tyrosine phosphatase receptor type f polypeptide-int
Recombinant Proteins
- Human
- Mouse
- Chicken
- Rhesus macaque
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
PPFIBP1 involved in several pathways and played different roles in them. We selected most pathways PPFIBP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PPFIBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
PPFIBP1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by PPFIBP1 itself. We selected most functions PPFIBP1 had, and list some proteins which have the same functions with PPFIBP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
PPFIBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPFIBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PPFIBP1.
YWHAG;YWHAB;YWHAQ;SFN;YWHAZ;Lats2
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References
