PPCDC
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Official Full Name
phosphopantothenoylcysteine decarboxylase -
Overview
Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes;and eukaryotes. PPCDC (EC 4.1.1.36), one of the last enzymes in this pathway, converts phosphopantothenoylcysteine to;4-prime-phosphopantetheine (Daugherty et al., 2002 (PubMed 11923312)). -
Synonyms
PPCDC;phosphopantothenoylcysteine decarboxylase;FLJ14585;MDS018;CoaC;MGC102190;1810057I13Rik;8430432M10Rik;COAC_HUMAN;PPC-DC;RGD1306267
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rat
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- E. coli
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PPCDC-1876H | Recombinant Human PPCDC, GST-tagged | E.coli | Human | GST | 1-204aa | |
| PPCDC-11041Z | Recombinant Zebrafish PPCDC | Mammalian Cell | Zebrafish | His |
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| PPCDC-13167M | Recombinant Mouse PPCDC Protein | Mammalian Cell | Mouse | His |
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| PPCDC-2841H | Recombinant Human PPCDC, His-tagged | E.coli | Human | His |
|
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| PPCDC-28672TH | Recombinant Human PPCDC, His-tagged | E.coli | Human | His | 204 amino acids |
|
| PPCDC-446H | Recombinant Human PPCDC protein, His-tagged | E.coli | Human | His | Met1-Ser204 |
|
| PPCDC-2982HCL | Recombinant Human PPCDC 293 Cell Lysate | HEK293 | Human | Non |
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| Ppcdc-1964M | Recombinant Mouse Ppcdc Protein, His-tagged | E.coli | Mouse | His | Met1-Ser204 |
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| Ppcdc-1965R | Recombinant Rat Ppcdc Protein, His-tagged | E.coli | Rat | His | Met1-Ser242 |
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| Ppcdc-5033M | Recombinant Mouse Ppcdc Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| PPCDC-6111H | Recombinant Human PPCDC protein, His-tagged | E. coli | Human | His | 219aa(including fusion tag) |
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| PPCDC-6972M | Recombinant Mouse PPCDC Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PPCDC-6972M-B | Recombinant Mouse PPCDC Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PPCDC involved in several pathways and played different roles in them. We selected most pathways PPCDC participated on our site, such as Pantothenate and CoA biosynthesis,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPCDC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | CYP2P6,CES1C,CYP51,ITPKC,GAL3ST1,PIGC,COX17,RDH12,QRSL1,MTMR1B |
| Pantothenate and CoA biosynthesis | UPB1,PANK3,COASY,AASDHPPT,VNN2,BCAT2,BCAT1,PPCS,DPYS,PANK1B |
Protein Function
PPCDC has several biochemical functions, for example, phosphopantothenoylcysteine decarboxylase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPCDC itself. We selected most functions PPCDC had, and list some proteins which have the same functions with PPCDC. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PLEKHN1,SIN3B,GOLGA2,SLC7A11,STOM,CHCHD6,GPSM3,EIF4E2,PFDN4,ITPR3 |
Interacting Protein
PPCDC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPCDC here. Most of them are supplied by our site. Hope this information will be useful for your research of PPCDC.
PPIG;FOXR1;SREK1IP1;WDYHV1;TXN2;ZNF232;DBI;PSMA1
Resources
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References
- Olzhausen, J; Moritz, T; et al. Molecular characterization of the heteromeric coenzyme A-synthesizing protein complex (CoA-SPC) in the yeast Saccharomyces cerevisiae. FEMS YEAST RESEARCH 13:565-573(2013).
- Xiang, Z; et al. DFT study on the reaction of the alpha-amino acid anion catalyzed by the aldehyde: Decarboxylation vs. intramolecular CO2 transfer. COMPUTATIONAL AND THEORETICAL CHEMISTRY 1006:1-8(2013).
