POU5F1B
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Official Full Name
POU class 5 homeobox 1B -
Overview
This intronless gene was thought to be a transcribed pseudogene of POU class 5 homeobox 1, however, it has been reported that this gene can encode a functional protein. The encoded protein is nearly the same length as and highly similar to the POU class 5 homeobox 1 transcription factor, has been shown to be a weak transcriptional activator and may play a role in carcinogenesis and eye development. -
Synonyms
POU5F1B;POU class 5 homeobox 1B;OTF3P1, POU class 5 homeobox 1 pseudogene 1 , POU domain class 5, transcription factor 1 pseudogene 1 , POU5F1P1;putative POU domain, class 5, transcription factor 1B;OTF3C;class 5;transcription factor 1B;Octamer-binding protein 3-like;Octamer-binding transcription factor 3-like;OTF3P1;P5F1B_HUMAN;POU5F1P1;POU5FLC20;POU5FLC8;Putative POU domain;POU 5 domain protein;POU class 5 homeobox 1 pseudogene 1;POU domain transcription factor Oct-4;octamer binding protein 3_like sequence;POU domain transcription factor OCT4-pg1;POU domain, class 5, transcription factor 1 pseudogene 1;OCT4-PG1;POU5F1P4
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| POU5F1B-2603H | Recombinant Human POU5F1B Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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Involved Pathway
POU5F1B involved in several pathways and played different roles in them. We selected most pathways POU5F1B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with POU5F1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
POU5F1B has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by POU5F1B itself. We selected most functions POU5F1B had, and list some proteins which have the same functions with POU5F1B. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
POU5F1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POU5F1B here. Most of them are supplied by our site. Hope this information will be useful for your research of POU5F1B.
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References
- Rogounovitch, TI; Bychkov, A; et al. The Common Genetic Variant rs944289 on Chromosome 14q13.3 Associates with Risk of Both Malignant and Benign Thyroid Tumors in the Japanese Population. THYROID 25:333-340(2015).
- Hu, Z; Zhu, D; et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. NATURE GENETICS 47:158-163(2015).
