POU4F3
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Official Full Name
POU class 4 homeobox 3 -
Overview
This gene encodes a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. This protein is found in the retina and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in this gene are the cause of non-syndromic sensorineural deafness autosomal dominant type 15. -
Synonyms
POU4F3;POU class 4 homeobox 3;DFNA15, POU domain class 4, transcription factor 3;POU domain, class 4, transcription factor 3;BRN3C;class 4;transcription factor 3;Brain specific homeobox/POU domain protein 3C;Brain-3C;Brain-specific homeobox/POU domain protein 3C;BRN 3C;Brn-3C;DFNA 15;DFNA15;MGC138412;PO4F3_HUMAN;POU domain;POU domain class 4 transcription factor 3;OTTHUMP00000160092
Recombinant Proteins
- Human
- Mouse
- Chicken
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- His
- His&GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| POU4F3-1866H | Recombinant Human POU4F3, His-tagged | E.coli | Human | His | 99-184aa | |
| POU4F3-13147M | Recombinant Mouse POU4F3 Protein | Mammalian Cell | Mouse | His |
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| POU4F3-145H | Recombinant Human POU4F3 Protein, GST-HIS-tagged | E.coli | Human | His&GST |
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| POU4F3-6323C | Recombinant Chicken POU4F3 | Mammalian Cell | Chicken | His |
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| POU4F3-8870Z | Recombinant Zebrafish POU4F3 | Mammalian Cell | Zebrafish | His |
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| POU4F3-3001HCL | Recombinant Human POU4F3 293 Cell Lysate | HEK293 | Human | Non |
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| POU4F3-6957M | Recombinant Mouse POU4F3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| POU4F3-6957M-B | Recombinant Mouse POU4F3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
POU4F3 involved in several pathways and played different roles in them. We selected most pathways POU4F3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with POU4F3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
POU4F3 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,transcription factor activity, sequence-specific DNA binding,transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POU4F3 itself. We selected most functions POU4F3 had, and list some proteins which have the same functions with POU4F3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | HIST2H3A,AEBP2,IFI16,MITF,MYOD1,FEZF1,DLX4,TFAP4,MED1,ARNT2 |
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | GMEB1,NR1H4,MITFB,CRX,POU2F3,MEIS1,ELF1,NRL,HMGA2,TRP63 |
| transcription factor activity, sequence-specific DNA binding | ZFP551,MESPBA,ZSCAN12,ASCL1,FOXC1B,ZNF354A,TAF5L,FOXP3,HMGB2,ZBTB14 |
Interacting Protein
POU4F3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POU4F3 here. Most of them are supplied by our site. Hope this information will be useful for your research of POU4F3.
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