POU2F2

  • Official Full Name

    POU class 2 homeobox 2

  • Overview

    Oct-2 is a transcription factor of the POU homeo-domain family that binds to the Ig gene octamer sites, regulating B-cell-specific genes. These are involved in proliferation and differentiation and despite the scarce evidence for Oct-2 expression in T cel

  • Synonyms

    POU2F2;POU class 2 homeobox 2;OTF2, POU domain class 2, transcription factor 2;POU domain, class 2, transcription factor 2;OCT2;OTF-2;homeobox protein;octamer-binding protein 2;octamer-binding transcription factor 2;lymphoid-restricted immunoglo

Recombinant Proteins

  • Mouse
  • Human
  • Rat
  • Mammalian Cell
  • E.coli
  • HEK293
  • His
  • His&T7
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
POU2F2-13139M Recombinant Mouse POU2F2 Protein Mammalian Cell Mouse His
POU2F2-7112H Recombinant Human POU2F2 protein, His & T7-tagged E.coli Human His&T7 Phe236~Leu459
Pou2f2-7113R Recombinant Rat Pou2f2 protein, His & T7-tagged E.coli Rat His&T7 Ala49~Ile288
POU2F2-1394HCL Recombinant Human POU2F2 cell lysate Human Non
POU2F2-4962H Recombinant Human POU2F2 Protein (Phe236-Thr398), N-His tagged E.coli Human His Phe236-Thr398
POU2F2-6951M Recombinant Mouse POU2F2 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
POU2F2-6951M-B Recombinant Mouse POU2F2 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    POU2F2 involved in several pathways and played different roles in them. We selected most pathways POU2F2 participated on our site, such as BCR signaling pathway,SIDS Susceptibility Pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with POU2F2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    SIDS Susceptibility Pathways KCNH2,MECP2,DEAF1,SCN3B,FOXM1,CDCA7L,ASCL1,POU3F2,ECE1,CC2D1A
    BCR signaling pathway IBTK,DOK1,PAG1,NETO2,CSK,MALT1,MAP4K1,CSNK2A1

    Protein Function

    POU2F2 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,protein domain specific binding,sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POU2F2 itself. We selected most functions POU2F2 had, and list some proteins which have the same functions with POU2F2. You can find most of the proteins on our site.

    Function Related Protein
    transcription factor activity, sequence-specific DNA binding OTX1A,ZFP354A,STAT3,ZIC3,TEFB,UBN2A,SMAD6A,CNOT7,CRX,RUNX2A
    protein domain specific binding YWHABL,MPP5,KPNB1,ITGA3,ANGEL1,YWHAG1,NLRP1,PTPN11,CA,ICA1
    transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding CEBPB,GMEB1,FOXJ1,DBP,FOXK2,MAFB,ZFAT,NR4A3,SOX1,NEUROG3
    sequence-specific DNA binding HOXC12B,POU2F3,MAFK,NKX1.2LA,DLX3B,ZFP536,LHX6,HOXD9A,TBX5,RXRBA
    RNA polymerase II core promoter proximal region sequence-specific DNA binding TBX3,MEF2B,CREB3,HOXA10,ZNF331,ZNF718,FOXI1,FOSL2,HIST2H3A,TXK

    Interacting Protein

    POU2F2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POU2F2 here. Most of them are supplied by our site. Hope this information will be useful for your research of POU2F2.

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