POU2AF1
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Official Full Name
POU class 2 associating factor 1 -
Overview
Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers. -
Synonyms
POU2AF1;POU class 2 associating factor 1;POU domain class 2, associating factor 1;POU domain class 2-associating factor 1;OBF1;BOB-1;OCA-B;OCT-binding factor 1;B-cell-specific coactivator OBF-1;POU domain, class 2, associating factor 1;BOB1;OCAB;OBF-1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| POU2AF1-27491TH | Recombinant Human POU2AF1, His-tagged | E.coli | Human | His | 256 amino acids |
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| POU2AF1-3570H | Recombinant Human POU2AF1, His-tagged | E.coli | Human | His |
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| POU2AF1-5749C | Recombinant Chicken POU2AF1 | Mammalian Cell | Chicken | His |
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| POU2AF1-3004HCL | Recombinant Human POU2AF1 293 Cell Lysate | HEK293 | Human | Non |
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Involved Pathway
POU2AF1 involved in several pathways and played different roles in them. We selected most pathways POU2AF1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with POU2AF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
POU2AF1 has several biochemical functions, for example, DNA binding,protein binding,transcription coactivator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by POU2AF1 itself. We selected most functions POU2AF1 had, and list some proteins which have the same functions with POU2AF1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription coactivator activity | MED21,NR1I3,HINFP,ZSCAN1,TAF12,MED17,NEUROD1,NRIP1,SOX10,ATXN7L3 |
| transcription cofactor activity | SND1,MED30,ZNF710,LPXN,BTG1,MED13,MSX2,AIRE,TFDP2,ZMYND11 |
| DNA binding | JUN,HOXB1,ARX,SOX19B,ZBED3,ZNF333,ZNF222,AKAP8L,ZNF18,CHD6 |
| protein binding | RASD1,TXN,RAB23,TSPO,SIK3,GPS1,CETN2,EEF1A2,ELK4,TXLNB |
Interacting Protein
POU2AF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POU2AF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of POU2AF1.
SIAH1;Syk;SYK
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