POLR2G
-
Official Full Name
polymerase (RNA) II (DNA directed) polypeptide G -
Overview
This gene encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein functions in transcription initiation, and is also thought to help stabilize transcribing polyermase molecules during elongation. -
Synonyms
POLR2G;polymerase (RNA) II (DNA directed) polypeptide G;DNA-directed RNA polymerase II subunit RPB7;hRPB19;hsRPB7;RPB7;DNA directed RNA polymerase II 19 kDa polypeptide;DNA directed RNA polymerase II subunit G;DNA directed RNA polymerase II subunit RPB7;MGC138367;MGC138369;RNA polymerase II subunit B7;OTTHUMP00000236339;RNA polymerase II 19 kDa subunit;RNA polymerase II seventh subunit;DNA-directed RNA polymerase II subunit G;DNA-d;RPB19
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cell
- HEK293
- His
- Non
- His&Fc&Avi
Involved Pathway
POLR2G involved in several pathways and played different roles in them. We selected most pathways POLR2G participated on our site, such as Purine metabolism,Pyrimidine metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with POLR2G were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | HAO2,PYCR1B,GLCEA,KLF15,FH1,NDUFA12,CELL,ASNS,AKR1B1,CBR3 |
| Epstein-Barr virus infection | HLA-DRB5,FCER2,SPI1,CR2,HLA-DPB1,POLR3H,HLA-B,TAB2,TBPL1,AKAP8L |
| Huntingtons disease | NDUFB2,mt-Atp8,DNALC4,NDUFB8,POLR2D,COX5B,NDUFS7,ATP5G1,DNAI2,DCTN2 |
| Pyrimidine metabolism | ENTPD3,POLR2J2,NT5C2A,PNP5A,NT5C3A,UCK1,NT5C2B,CANT1B,NT5C1B,NME4 |
| RNA polymerase | POLR3B,POLR2L,POLR3A,POLR3K,POLR2J,POLR2C,POLR2B,ZNRD1,POLR2A,POLR1D |
| Purine metabolism | POLR1C,POLA2,NT5C3L,NPR2,NT5E,FHIT,POLE4,PRPS2,NT5M,PDE4D |
Protein Function
POLR2G has several biochemical functions, for example, contributes_to DNA-directed RNA polymerase activity,single-stranded DNA binding,single-stranded RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POLR2G itself. We selected most functions POLR2G had, and list some proteins which have the same functions with POLR2G. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| translation initiation factor binding | ZNF259,DDX3X,TBL2,TRIM32,EIF2B4,LIN28A,CELF1,POLR2D,POLR2GL,LARP1 |
| contributes_to DNA-directed RNA polymerase activity | POLR2GL |
| single-stranded DNA binding | TDP1,SUB1,ERCC5,POLR2GL,ERCC4,HNRNPK,PEO1,CRY2,SSBP2,PCBP1 |
| single-stranded RNA binding | IFIH1,STRBP,EIF2C3,RBMX,JMJD6,CBX4,AGO3,A1CF,LSM14A,ENDOV |
Interacting Protein
POLR2G has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POLR2G here. Most of them are supplied by our site. Hope this information will be useful for your research of POLR2G.
MED26;MED19;MED29;USP45;WDR48;USP44;MCM3AP;PRKRA;MYOD1;STK19;TNNC1;NTRK2;NOTCH2NL;DDX54;FNDC4
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