POLR1A
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Official Full Name
polymerase (RNA) I polypeptide A
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| POLR1A-1837H | Recombinant Human POLR1A, GST-tagged | E.coli | Human | GST | C-280aa | |
| POLR1A-13086M | Recombinant Mouse POLR1A Protein | Mammalian Cells | Mouse | His |
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| POLR1A-4567R | Recombinant Rat POLR1A Protein | Mammalian Cells | Rat | His |
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| POLR1A-4227R | Recombinant Rat POLR1A Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| POLR1A-4227R-B | Recombinant Rat POLR1A Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| POLR1A-6916M | Recombinant Mouse POLR1A Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| POLR1A-6916M-B | Recombinant Mouse POLR1A Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
POLR1A involved in several pathways and played different roles in them. We selected most pathways POLR1A participated on our site, such as Purine metabolism,Pyrimidine metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with POLR1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | UPRT,CDS1,MDH1AA,ALAS1,SDS,FUT2,GLUD2,HSD17B3,DUT,PIGL |
| RNA polymerase | POLR2GL,POLR1D,POLR3D,POLR3GL,POLR3A,POLR1B,POLR2A,POLR2I,POLR2C,POLR2B |
| Pyrimidine metabolism | CTPS2,TK2,ENTPD1,TK1,CMPK1,PRIM2,POLR1E,POLR3GLB,UCK2B,POLD4 |
| Purine metabolism | ZNRD1,PPAT,NT5C3B,ADCY1A,POLE2,NME6,POLR2C,PAICS,CANT1,POLR3D |
Protein Function
POLR1A has several biochemical functions, for example, DNA binding,contributes_to RNA polymerase I activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POLR1A itself. We selected most functions POLR1A had, and list some proteins which have the same functions with POLR1A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PELP1,KLHDC5,SOD1,TMEM30B,BLOC1S2,CA1,ING5,MED9,CD164,NFATC3 |
| contributes_to RNA polymerase I activity | POLR2EB,POLR2F,POLR2K,ZNRD1,POLR2E,POLR1E,POLR2L,POLR2H,TWISTNB,POLR1D |
| DNA binding | NR2F1A,TADA2B,HELT,FOXA,MEF2CA,ANKRD1,RARAA,SETDB1,ZFP292,CMYB |
| zinc ion binding | MICAL2,MSRB3,ZNF253,Adam6,TRIM23,UBR1,RNF26,ZDHHC5A,TRIM31,MDM2 |
Interacting Protein
POLR1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POLR1A here. Most of them are supplied by our site. Hope this information will be useful for your research of POLR1A.
POLR1B;ERBB2;TCF4
Resources
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References
- Holt, R; Sykes, NH; et al. CNVs leading to fusion transcripts in individuals with autism spectrum disorder. EUROPEAN JOURNAL OF HUMAN GENETICS 20:1141-1147(2012).
- Marques, TEBS; de Mendonca, LR; et al. Validation of Suitable Reference Genes for Expression Studies in Different Pilocarpine-Induced Models of Mesial Temporal Lobe Epilepsy. PLOS ONE 8:-(2013).
