POGZ
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Official Full Name
pogo transposable element with ZNF domain -
Overview
The protein encoded by this gene appears to be a zinc finger protein containing a transposase domain at the C-terminus. This protein was found to interact with the transcription factor SP1 in a yeast two-hybrid system. Alternatively spliced transcript variants encoding distinct isoforms have been observed. -
Synonyms
POGZ;pogo transposable element with ZNF domain;KIAA0461;putative protein product of Nbla00003;SUHW5;suppressor of hairy wing homolog 5;zinc finger protein 280E;ZNF280E;ZNF635m;MGC71543;POGZ_HUMAN;suppressor of hairy wing homolog;Zinc finger protein 635;ZNF635
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| POGZ-3501R | Recombinant Rhesus monkey POGZ Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| POGZ-1387HCL | Recombinant Human POGZ cell lysate | Human | Non |
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| POGZ-2406H | Recombinant Human POGZ Protein, DDK-tagged | Insect Cell | Human | Flag |
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| POGZ-3319R | Recombinant Rhesus Macaque POGZ Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| POGZ-3319R-B | Recombinant Rhesus Macaque POGZ Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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Involved Pathway
POGZ involved in several pathways and played different roles in them. We selected most pathways POGZ participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with POGZ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
POGZ has several biochemical functions, for example, DNA binding,metal ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POGZ itself. We selected most functions POGZ had, and list some proteins which have the same functions with POGZ. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | ZFP583,HMGXB3,PROX1B,ZFP92,HIST1H2BK,HIST1H2BN,KLF12,FOXL2,ZNF707,HIST2H2AA4 |
| protein binding | PAF1,FOXJ2,KATNAL1,ZBTB1,NKX2-5,FBXO25,SPG7,SNAP29,TFB1M,PIK3R2 |
| metal ion binding | CREB5,KIN,LEPREL1,MEP1A.1,MGRN1A,SEC23IP,ASXL3,ZNF713,ZNF155,CLCA1 |
Interacting Protein
POGZ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POGZ here. Most of them are supplied by our site. Hope this information will be useful for your research of POGZ.
CBX5;HGS;ZBTB24;DAB1;POU2F1;NFYA
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References
- Cermakova, K; Tesina, P; et al. Validation and Structural Characterization of the LEDGF/p75-MLL Interface as a New Target for the Treatment of MLL-Dependent Leukemia. CANCER RESEARCH 74:5139-5151(2014).
- Hendrix, J; van Heertum, B; et al. Dynamics of the Ternary Complex Formed by c-Myc Interactor JPO2, Transcriptional Co- activator LEDGF/p75, and Chromatin. JOURNAL OF BIOLOGICAL CHEMISTRY 289:12494-12506(2014).
