PNPLA4
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Official Full Name
patatin-like phospholipase domain containing 4 -
Overview
This gene encodes a member of the patatin-like family of phospholipases. The encoded enzyme has both triacylglycerol lipase and transacylase activities and may be involved in adipocyte triglyceride homeostasis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome Y. -
Synonyms
PNPLA4;patatin-like phospholipase domain containing 4;patatin-like phospholipase domain-containing protein 4;DXS1283E;GS2;IPLA2 eta;calcium independent phospholipases A2 eta
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PNPLA4-261H | Recombinant Human PNPLA4 Protein, His-tagged | E.coli | Human | His |
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| PNPLA4-3495R | Recombinant Rhesus monkey PNPLA4 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| PNPLA4-3858C | Recombinant Chicken PNPLA4 | Mammalian Cell | Chicken | His |
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| PNPLA4-5586Z | Recombinant Zebrafish PNPLA4 | Mammalian Cell | Zebrafish | His |
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| PNPLA4-3067HCL | Recombinant Human PNPLA4 293 Cell Lysate | HEK293 | Human | Non |
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| PNPLA4-3313R | Recombinant Rhesus Macaque PNPLA4 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| PNPLA4-3313R-B | Recombinant Rhesus Macaque PNPLA4 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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Involved Pathway
PNPLA4 involved in several pathways and played different roles in them. We selected most pathways PNPLA4 participated on our site, such as Retinol metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PNPLA4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Retinol metabolism | AOX4,UGT1A3,CYP3A41B,LRATA,CYP2C45,DHRS4L2,CYP2C37,RDH10B,DHRS3B,CYP1A |
Protein Function
PNPLA4 has several biochemical functions, for example, molecular_function,triglyceride lipase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PNPLA4 itself. We selected most functions PNPLA4 had, and list some proteins which have the same functions with PNPLA4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | PORCNL,BEST2,NKX2-4,SPECC1L,CRYGM2D17,ZMYND17,PCED1A,TRP53I11,FAM180A,PLEKHM3 |
| triglyceride lipase activity | PNLIPRP3,AADAC,LIPE,Cel,PNLIPRP2,LIPC,CEL.1,CES5A,PNPLA3,CES1D |
Interacting Protein
PNPLA4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PNPLA4 here. Most of them are supplied by our site. Hope this information will be useful for your research of PNPLA4.
Resources
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References
- Murugesan, S; Goldberg, EB; et al. Identification of Diverse Lipid Droplet Targeting Motifs in the PNPLA Family of Triglyceride Lipases. PLOS ONE 8:-(2013).
- Meier, P; Gloekler, S; et al. G-CSF Induced Arteriogenesis in Humans: Molecular Insights into a Randomized Controlled Trial. CURRENT VASCULAR PHARMACOLOGY 11:38-46(2013).
