PNN
-
Official Full Name
pinin, desmosome associated protein -
Overview
Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5CAGGTG-3. Capable of reversing CTBP1-mediated transcription repression. Component of a splicing-dependent multiprotein exon jun -
Synonyms
PNN;pinin, desmosome associated protein;pinin;memA;140 kDa nuclear and cell adhesion-related phosphoprotein;Desmosome-associated protein;Domain-rich serine protein;DRS;DRS protein;DRSP;Melanoma metastasis clone A protein;Nuclear protein SDK3;PININ_HUMAN;SR like protein;SR-like protein;OTTHUMP00000178906;neutrophil protein;SDK3
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PNN-13036M | Recombinant Mouse PNN Protein | Mammalian Cell | Mouse | His |
|
|
| PNN-30966TH | Recombinant Human PNN | Wheat Germ | Human | Non | 100 amino acids |
|
| PNN-7688Z | Recombinant Zebrafish PNN | Mammalian Cell | Zebrafish | His |
|
|
| PNN-3074HCL | Recombinant Human PNN 293 Cell Lysate | HEK293 | Human | Non |
|
|
| PNN-6885M | Recombinant Mouse PNN Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| PNN-6885M-B | Recombinant Mouse PNN Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
Involved Pathway
PNN involved in several pathways and played different roles in them. We selected most pathways PNN participated on our site, such as RNA transport,mRNA surveillance pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PNN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA transport | THOC7,NCBP2,NXT2,EEF1A1L1,PABPC4,EEF1A2,EIF5B,ALYREF,NUP93,PABPC5 |
| mRNA surveillance pathway | FIP1L1,FIP1L1B,PPP2R5CB,PPP1CC,PPP1CA,PPP1CAA,RNMT,PABPC1A,PPP2CB,PPP2R5D |
Protein Function
PNN has several biochemical functions, for example, DNA binding,poly(A) RNA binding,structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PNN itself. We selected most functions PNN had, and list some proteins which have the same functions with PNN. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | KHDRBS1,TBL2,TPD52L2,EIF3D,ADD1,Txn1,RSL24D1,MRPL45,KIAA1429,HNRNPUL1 |
| structural molecule activity | MPZL1,SPRR2D,DSP,COPB1,BVES,SPRR1A,CYT1,CLDN16,RLN3B,LAMA2 |
| DNA binding | ZFP292,ZNF143B,ZFP326,ZNF654,SP9,CHD9,TFDP2,HMGXB3,SS18L1,ZNF83 |
Interacting Protein
PNN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PNN here. Most of them are supplied by our site. Hope this information will be useful for your research of PNN.
YWHAG;SNW1;Srek1;SNIP1;FOS;YWHAZ;RNPS1;SF3A2;NFKBIL1;narH;PDPK1;UBE2I;q5nem8_fratt;TOE1;VAMP8;MED19
Resources
Related Services
Related Products
References
- Dick, G; Tan, CL; et al. Semaphorin 3A Binds to the Perineuronal Nets via Chondroitin Sulfate Type E Motifs in Rodent Brains. JOURNAL OF BIOLOGICAL CHEMISTRY 288:27384-27395(2013).
- Madinier, A; Quattromani, MJ; et al. Enriched Housing Enhances Recovery of Limb Placement Ability and Reduces Aggrecan-Containing Perineuronal Nets in the Rat Somatosensory Cortex after Experimental Stroke. PLOS ONE 9:-(2014).
