PLXNC1
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Official Full Name
plexin C1 -
Overview
This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene. -
Synonyms
PLXNC1;plexin C1;plexin-C1;CD232;VESPR;PLXC1_HUMAN;Virus-encoded semaphorin protein receptor;plexin (semaphorin receptor);receptor for viral semaphorin protein;receptor for virally-encoded semaphorin;PLXN-C1
Recombinant Proteins
- Human
- Rhesus macaque
- Mouse
- Mammalian Cells
- E.coli
- HEK293
- His
- Myc&DDK
- Avi&His&Fc
- His&Fc&Avi
Involved Pathway
PLXNC1 involved in several pathways and played different roles in them. We selected most pathways PLXNC1 participated on our site, such as Axon guidance,Developmental Biology,Other semaphorin interactions, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLXNC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Semaphorin interactions | DPYSL2,SEMA4D,RND1L,DPYSL5B,SEMA3A,NRP1A,CRMP1,SEMA3AA,DPYSL5A,DPYSL3 |
| Other semaphorin interactions | SEMA4D,PLXND1 |
| Developmental Biology | ARPC2,NRG3,AP2A2,CFL1,CACNG8A,KBTBD7,EFNA2,CDK19,CTNNA2,RHOB |
| Axon guidance | ITGB1,RAC3,TRPC4,EPHB4A,LIMK2,TRPC5,ST8SIA2,SCN3A,CSNK2A1,PAK3 |
Protein Function
PLXNC1 has several biochemical functions, for example, protein binding,receptor binding,semaphorin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PLXNC1 itself. We selected most functions PLXNC1 had, and list some proteins which have the same functions with PLXNC1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| semaphorin receptor activity | PLXNB2A,NRP1,NRP1B,NRP2B,Plxna2,NRP2A,PLXNB2B,NRP2,PLXND1,PLXNA1 |
| protein binding | ABL1,PDGFC,KIAA1191,SURF1,POLD2,GLTP,EFHC2,CDC42EP5,MPDZ,NUS1 |
| receptor binding | GUSB,NPFFL,FYNB,CXCL12,WNT5B,LPL,SLC27A2,PECI,SRI,FZD1 |
Interacting Protein
PLXNC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLXNC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLXNC1.
SEMA7A;EVM139
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