PLS1
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Official Full Name
plastin 1 -
Overview
Fimbrin is an actin cross-linking protein important in the formation of filopodia.Fimbrin belongs to the calponin homology (CH) domain superfamily of actin cross-linking proteins. Like other members of this superfamily, which include α-actinin, β-spectrin, dystrophin, ABP-120 and filamin, it has a conserved 27 kDa actin-binding domain that contains a tandem duplication of a sequence that is homologous to calponin. In addition to cross-linking actin filaments into bundles and networks, CH domains also bind intermediate filaments and some signal transduction proteins to the actin cytoskeleton. Structural comparison of actin filaments and fimbrin CH domain-decorated actin filaments has revealed changes in the actin structure due to fimbrin-mediated cross-linking that may affect the actin filaments" affinity for other actin-binding proteins and may be part of the regulation of the cytoskeleton itself. -
Synonyms
Fimbrin;I Fimbrin;I Plastin;Intestine specific plastin;Plastin 1 (I isoform);Plastin 1;Plastin1;Fimbrin (p67);PLS1
Recombinant Proteins
- Zebrafish
- Chicken
- Human
- Mouse
- Zea Mays
- Mammalian Cell
- HEK293
- HEK293T
- E.coli
- E.coli expression system
- His
- Non
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PLS1-10253Z | Recombinant Zebrafish PLS1 | Mammalian Cell | Zebrafish | His |
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| PLS1-6899C | Recombinant Chicken PLS1 | Mammalian Cell | Chicken | His |
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| PLS1-3097HCL | Recombinant Human PLS1 293 Cell Lysate | HEK293 | Human | Non |
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| Pls1-211M | Recombinant Mouse Pls1 Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| PLS1-2344H | Recombinant Human PLS1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| PLS1-2598H | Recombinant Human PLS1 Protein, His-tagged | E.coli | Human | His | Thr108-Lys380 |
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| PLS1-3606H | Recombinant Human PLS1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| RFL33309ZF | Recombinant Full Length Zea Mays 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Pls1(Pls1) Protein, His-Tagged | E.coli expression system | Zea Mays | His | Full L. Full Length (1-374) |
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Involved Pathway
PLS1 involved in several pathways and played different roles in them. We selected most pathways PLS1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PLS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
PLS1 has several biochemical functions, for example, actin filament binding,calcium ion binding,structural constituent of cytoskeleton. Some of the functions are cooperated with other proteins, some of the functions could acted by PLS1 itself. We selected most functions PLS1 had, and list some proteins which have the same functions with PLS1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin filament binding | CORO6,FMNL1,MYH11,LIMA1,LASP1,PLDN,FSCN1,CORO2B,ABL2,HAND2 |
| calcium ion binding | DSG2,CIB3,MYL4,NOTCH1A,NOTCH1,CDHR1,CDH2,SYTL4,CAPN9,SLIT1 |
| structural constituent of cytoskeleton | SPTB,LOR,NGS,AGRN,KRT16,BICD1,COX4I2,ACTB,ACTG1,KRT5 |
Interacting Protein
PLS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLS1.
ARF6;pi3p;1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate;15-deoxy-delta(12,14;MYH9;Myh9
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