PLIN
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Official Full Name
perilipin -
Overview
The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. -
Synonyms
PLIN;perilipin
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Involved Pathway
PLIN involved in several pathways and played different roles in them. We selected most pathways PLIN participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PLIN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
PLIN has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by PLIN itself. We selected most functions PLIN had, and list some proteins which have the same functions with PLIN. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
PLIN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLIN here. Most of them are supplied by our site. Hope this information will be useful for your research of PLIN.
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References
- MacPherson, REK; Castelli, LM; et al. A Maternal High Fat Diet Has Long-Lasting Effects on Skeletal Muscle Lipid and PLIN Protein Content in Rat Offspring at Young Adulthood. LIPIDS 50:205-217(2015).
- Sanz, A; Serrano, C; et al. Novel polymorphisms in the 5 ' UTR of FASN, GPAM, MC4R and PLIN1 ovine candidate genes: Relationship with gene expression and diet. SMALL RUMINANT RESEARCH 123:70-74(2015).
