PLEKHG5
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Official Full Name
pleckstrin homology domain containing, family G (with RhoGef domain) member 5 -
Overview
This gene encodes a protein that activates the nuclear factor kappa B (NFKB1) signaling pathway. Multations in this gene have been found in a family with distal spinal muscular atrophy. -
Synonyms
PLEKHG5;pleckstrin homology domain containing, family G (with RhoGef domain) member 5;pleckstrin homology domain-containing family G member 5;KIAA0720;NFkB activating protein;novel PH domain-containing protein;PH domain-containing family G member 5
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PLEKHG5-1783H | Recombinant Human PLEKHG5, GST-tagged | E.coli | Human | GST | 597-930aa | |
| PLEKHG5-4518R | Recombinant Rat PLEKHG5 Protein | Mammalian Cell | Rat | His |
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| PLEKHG5-4178R | Recombinant Rat PLEKHG5 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| PLEKHG5-4178R-B | Recombinant Rat PLEKHG5 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
PLEKHG5 involved in several pathways and played different roles in them. We selected most pathways PLEKHG5 participated on our site, such as Pathways in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLEKHG5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Pathways in cancer | PIAS2,LAMC1,GNAS,KIT,PRKCA,RXRB,ITGAV,CKS2,BMP4,PRKACB |
Protein Function
PLEKHG5 has several biochemical functions, for example, Rho guanyl-nucleotide exchange factor activity,signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PLEKHG5 itself. We selected most functions PLEKHG5 had, and list some proteins which have the same functions with PLEKHG5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| Rho guanyl-nucleotide exchange factor activity | PLEKHG2,FARP1,C9orf100,PLEKHG4,ARHGEF37,ARHGEF9,ARHGEF18A,ARHGEF1B,FGD4A,QUO |
| signal transducer activity | OLFR481,TAS2R200.1,RGRA,IL15RA,TAS2R120,CALCRLA,GPR173,PTK2B,MIER1B,ADRA2DB |
Interacting Protein
PLEKHG5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLEKHG5 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLEKHG5.
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