PLCL1
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Official Full Name
phospholipase C-like 1 -
Synonyms
PLCL1;phospholipase C-like 1;phospholipase C, epsilon , PLCE;inactive phospholipase C-like protein 1;phospholipase C related;but catalytically inactive protein;PLC L;PLCL;PRIP;PLC-L1;phospholipase C, epsilon;phospholipase C-deleted in lung carc
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cell
- HEK293
- GST
- His&T7
- His
- His&Fc&Avi
Involved Pathway
PLCL1 involved in several pathways and played different roles in them. We selected most pathways PLCL1 participated on our site, such as GABAergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLCL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| GABAergic synapse | SRC,GLS2,SLC6A13,GABBR1,GABARAP,GNAI3,GNGT2,GABRB1,GABRA3,PRKACB |
Protein Function
PLCL1 has several biochemical functions, for example, GABA receptor binding,inositol 1,4,5 trisphosphate binding,phosphatidylinositol phospholipase C activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PLCL1 itself. We selected most functions PLCL1 had, and list some proteins which have the same functions with PLCL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phospholipase C activity | PLCB2,PLCB4,PLCG2,ADORA1,PLCG1,PLCH2,PDIA3,PLCE1,PLCB3 |
| inositol 1,4,5 trisphosphate binding | TRPC7A,TRPC6A,TRPC2B,TRPC6,TRPC4,RPH3A,TRPC3,TRPC1,CYTH2,TRPC7 |
| phosphatidylinositol phospholipase C activity | PLCG2,PLCD1,EDNRA,PLCD1B,CHRM1,PLCD3A,CCKBR,PLCD4,BDKRB2,PLCB3 |
| GABA receptor binding | GABARAPA,PPP2CA,TRAK1,ARFGEF2,AKAP5,GABRB1,JAKMIP1,GABARAPL2,GABRG1,GABARAP |
| signal transducer activity | CRKL,TAAR6,TRHRB,TAAR14E,OPN1MW1,FPR3,TAS2R113,TAAR14H,ADRB3B,GNA13B |
Interacting Protein
PLCL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLCL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLCL1.
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References
- Miller, FW; Cooper, RG; et al. Genome-Wide Association Study of Dermatomyositis Reveals Genetic Overlap With Other Autoimmune Disorders. ARTHRITIS AND RHEUMATISM 65:3239-3247(2013).
- Iwai, LK; Payne, LS; et al. Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants. BIOCHEMICAL JOURNAL 454:501-513(2013).
