PKP3
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Official Full Name
Plakophilin 3 -
Overview
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways. -
Synonyms
PKP3;plakophilin 3;Plakophilin-3;plakophilin 3b;OTTHUMP00000147609
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PKP3-1748H | Recombinant Human PKP3, His-tagged | E.coli | Human | His | 170-400AA | |
| PKP3-12880M | Recombinant Mouse PKP3 Protein | Mammalian Cell | Mouse | His |
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| PKP3-1886H | Recombinant Human PKP3 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| PKP3-3267H | Recombinant Human PKP3 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Pkp3-4892M | Recombinant Mouse Pkp3 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| PKP3-6792M | Recombinant Mouse PKP3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PKP3-6792M-B | Recombinant Mouse PKP3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PKP3 involved in several pathways and played different roles in them. We selected most pathways PKP3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PKP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PKP3 has several biochemical functions, for example, alpha-catenin binding,cell adhesion molecule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PKP3 itself. We selected most functions PKP3 had, and list some proteins which have the same functions with PKP3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| alpha-catenin binding | NUMB,CDH2,JUB,AJUBA,JUPA,PKP2,JUP,CDH24,VCL,CTNNB1 |
| cell adhesion molecule binding | ITGA4,EZR,PVR,SDCBP,CADM1A,ITGAL,MSN,PTPRD,CADM4,ITGB2 |
Interacting Protein
PKP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PKP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PKP3.
ESR2;SFN;ssrna_ug;Sec24c;SEC16A;MAST3;MCM7;MATR3;CLTC;SNW1;GTSE1;RBM8A
Resources
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References
- Kalantari-Dehaghi, M; Anhalt, GJ; et al. Pemphigus Vulgaris Autoantibody Profiling by Proteomic Technique. PLOS ONE 8:-(2013).
- Muhmer, M; Ditthardt, D; et al. An alternative promoter of the human plakophilin-3 gene controls the expression of the new isoform PKP3b. CELL AND TISSUE RESEARCH 355:143-162(2014).
