PKNOX1
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Official Full Name
PBX/knotted 1 homeobox 1 -
Overview
Homeobox protein PKNOX1 is a protein that in humans is encoded by the PKNOX1 gene. -
Synonyms
PKNOX1;PBX/knotted 1 homeobox 1;homeobox protein PKNOX1;PREP1;human homeobox containing protein;Pbx regulating protein 1;PBX/knotted homeobox 1;homeobox protein PREP-1;Pbx regulating protein-1;human homeobox-containing protein;pkonx1c
Recombinant Proteins
- Mouse
- Human
- Rhesus macaque
- Mammalian Cell
- E.coli
- HEK293
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PKNOX1-12876M | Recombinant Mouse PKNOX1 Protein | Mammalian Cell | Mouse | His |
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| PKNOX1-208H | Recombinant Human PKNOX1, His-tagged | E.coli | Human | His | 1-436aa |
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| PKNOX1-3450R | Recombinant Rhesus monkey PKNOX1 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| PKNOX1-3148HCL | Recombinant Human PKNOX1 293 Cell Lysate | HEK293 | Human | Non |
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| PKNOX1-3268R | Recombinant Rhesus Macaque PKNOX1 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| PKNOX1-3268R-B | Recombinant Rhesus Macaque PKNOX1 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| PKNOX1-6789M | Recombinant Mouse PKNOX1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PKNOX1-6789M-B | Recombinant Mouse PKNOX1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PKNOX1 involved in several pathways and played different roles in them. We selected most pathways PKNOX1 participated on our site, such as SIDS Susceptibility Pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PKNOX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| SIDS Susceptibility Pathways | YBX1,RUNX3,SST,PLP1,KCNJ8,POU2F2,SCN3B,KCNH2,LMX1B,EN1 |
Protein Function
PKNOX1 has several biochemical functions, for example, protein heterodimerization activity,sequence-specific DNA binding,transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PKNOX1 itself. We selected most functions PKNOX1 had, and list some proteins which have the same functions with PKNOX1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, sequence-specific DNA binding | SIX4,DBPA,MYCN,FOXO1B,REST,ZNF19,MAFG,MAFGB,HIC1,TCF19 |
| sequence-specific DNA binding | NR1D1,NR6A1B,TSN,HOXC3A,ESR2A,ZFP191,SIX2B,EVE1,HOXB13,HNF1B |
| protein heterodimerization activity | HIST1H2BD,DMRT1,CABYR,INHA,NOTCH4,HYPM,RELA,SOX32,BNIP3L,PAFAH1B2 |
| transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding | PLAGL1,NR1I2,RFX6,FOXO3,GATA1A,ONECUT3,TBX5,CEBPA,GATA6,PAX9 |
| transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | RFX3,PROX1,JUN,POU3F1,MEF2A,POU3F3,NFIX,SNAI2,TLE4,SOX10 |
Interacting Protein
PKNOX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PKNOX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PKNOX1.
PBX2;pp2_dna;MEIS2;PBX1;PBX1;PBX3;q9wmx2-pro_0000037548;mdm2_human_probe;Pbx2;Actb;Pbx1;Mybbp1a
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References
- Tran, S; Lamba, P; et al. SMADs and FOXL2 Synergistically Regulate Murine FSH beta Transcription Via a Conserved Proximal Promoter Element. MOLECULAR ENDOCRINOLOGY 25:1170-1183(2011).
- Tomoeda, M; Yuki, M; et al. Role of Meis1 in mitochondrial gene transcription of pancreatic cancer cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 410:798-802(2011).
