PKACa2
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Official Full Name
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Overview
The protein kinase A holoenzyme is a heterotetramer composed of two types of subunits: Catalytic and Regulatory. The Catalytic subunit contains the enzyme's active site. It also contains a domain that binds ATP and a domain that binds the regulatory subunit. The Regulatory subunit consists of two molecules which bind one another in an anti-parallel orientation to form a homodimer; for type I subunits- this binding is covalent via disulfide bonds. This subunit also has has two domains that bind cyclic AMP, a domain that interacts with a catalytic subunit, and an "auto-inhibitory" domain that serves as a substrate or pseudosubstrate for the catalytic subunit. -
Synonyms
Inactive Protein Kinase A holoenzyme type I alpha;Protein Kinase A holoenzyme type I alpha;PKACa2- RIa2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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| PKACa2-90 | Recombinant Inactive Protein Kinase A holoenzyme type I alpha | E.coli | Non |
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| PKACa2-91 | Recombinant Protein Kinase A holoenzyme type II alpha | E.coli | Non |
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Involved Pathway
PKACa2 involved in several pathways and played different roles in them. We selected most pathways PKACa2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PKACa2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
PKACa2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by PKACa2 itself. We selected most functions PKACa2 had, and list some proteins which have the same functions with PKACa2. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
PKACa2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PKACa2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PKACa2.
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