PJA2
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Official Full Name
praja ring finger 2 -
Overview
E3 ubiquitin-protein ligase Praja2 is an enzyme that in humans is encoded by the PJA2 gene. -
Synonyms
PJA2;praja ring finger 2;E3 ubiquitin-protein ligase Praja-2;E3 ubiquitin protein ligase Praja2;KIAA0438;Neurodap 1;Neurodap1;PJA 2;PJA2_HUMAN;Praja 2;Praja 2 RING H2 motif containing;Praja2;RING finger protein 131;RNF 131;RNF131;OTTHUMP00000158944;praja 2, RING-H2 motif containing
Recombinant Proteins
- Mouse
- Rat
- Human
- Mammalian Cells
- HEK293
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PJA2-12856M | Recombinant Mouse PJA2 Protein | Mammalian Cells | Mouse | His |
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| PJA2-4479R | Recombinant Rat PJA2 Protein | Mammalian Cells | Rat | His |
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| PJA2-3159HCL | Recombinant Human PJA2 293 Cell Lysate | HEK293 | Human | Non |
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| PJA2-4139R | Recombinant Rat PJA2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| PJA2-4139R-B | Recombinant Rat PJA2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| PJA2-6776M | Recombinant Mouse PJA2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PJA2-6776M-B | Recombinant Mouse PJA2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PJA2 involved in several pathways and played different roles in them. We selected most pathways PJA2 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with PJA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Immune System | SEC23A,KIF26A,AP1M2,EIF4G2,CSHL1,CLEC4A,RNF144B,MGC174152,DDX41,BTR16 |
| Class I MHC mediated antigen processing & | TRIM41,DZIP3,RNF4,LRRC41,LRSAM1,CYBB,NPEPPS,RNF138,TRIM11,ASB14 |
| Proteasome degradation | FBXO3,ASB3,UBE2E3,GAN,TRIM11,DZIP3,ASB17,TRIM69,VPRBP,RNF19B |
| Adaptive Immune System | VPRBP,CTSK,THEM4,FGF8B,CTSC,NPEPPS,MOV10,ASB10,ACTR1B,FCGR1B |
| presentation | ASB8,UBE2V2,SH3RF1,RNF34,ASB9,HECTD3,ASB6,TRIM69,KLHL20,PJA1 |
| Antigen processing: Ubiquitination & | UBR2,ARIH2,ASB9,RNF182,TRIM69,TRIM50,UBE2F,ASB17,UBE2U,PJA1 |
Protein Function
PJA2 has several biochemical functions, for example, ligase activity,protein kinase A catalytic subunit binding,protein kinase A regulatory subunit binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PJA2 itself. We selected most functions PJA2 had, and list some proteins which have the same functions with PJA2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | ADA,RNF144AA,RNF114,CRIP2,RNF11A,PRKCBB,LHX2B,MYLIPB,MSL2A,RNF113B |
| protein kinase A catalytic subunit binding | SOX9,GSK3B,PRKAR1A,PRKAR2A,PKIA,EZR,RYR2,GSK3A,PRKAR2B,CSK |
| protein kinase A regulatory subunit binding | AKAP8,AKAP6,RYR2,KCNQ1,EZR,ARFGEF2,C2orf88,AKAP7,ARFGEF1,ACBD3 |
| ligase activity | PIAS4,BRCA1,SHRPRBCK1R,SMURF1,PRP19,TRAF3,TRIML2,PIAS3,RNF216,PIAS1 |
| ubiquitin-protein transferase activity | RNF10,RNF144B,RNF13,ZFP91,RNF125,FBXL14B,LRSAM1,TRIM71,LMO7,MARCH8 |
| ubiquitin protein ligase activity | MYLIP,ARIH1L,UBE3B,FANCF,RNF121,G2E3,TMEM189,HECTD3,UBE2O,RNF165 |
Interacting Protein
PJA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PJA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PJA2.
PRKAR2A;USP46;UBE2L6;UBE2D1;UBE2D3;UBE2N;UBE2D2;q81vw1_bacan;fabF;UBE2W;UBE2D4;UBE2J1;UBXN7;UBXN1;FAF2;FAF1
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