PINX1

  • Official Full Name

    PIN2/TERF1 interacting, telomerase inhibitor 1

  • Overview

    Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.

  • Synonyms

    PINX1;PIN2/TERF1 interacting, telomerase inhibitor 1;PIN2/TERF1-interacting telomerase inhibitor 1;FLJ20565;liver related putative tumor suppressor;LPTL;LPTS;MGC8850;PIN2 interacting protein 1;67-11-3 protein;Hepatocellular carcinoma-related putative tumor suppressor;Liver-related putative tumor suppressor;OTTHUMP00000224984;OTTHUMP00000224985;OTTHUMP00000224986;OTTHUMP00000225053;OTTHUMP00000225054;Pin2-interacting protein X1;PINX1_HUMAN;Protein 67-11-3;TRF1-interacting protein 1;PIN2-interacting protein 1

Recombinant Proteins

  • Mouse
  • Zebrafish
  • Human
  • Rat
  • Mammalian Cell
  • E.coli
  • HEK293
  • HEK293T
  • His
  • Non
  • His&Fc&Avi
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
PINX1-12822M Recombinant Mouse PINX1 Protein Mammalian Cell Mouse His
PINX1-2073Z Recombinant Zebrafish PINX1 Mammalian Cell Zebrafish His
PINX1-30965TH Recombinant Human PINX1, His-tagged E.coli Human His Full L. 1-328 a.a.
PINX1-404H Recombinant Human PIN2-interacting protein 1, His-tagged E.coli Human His
PINX1-4467R Recombinant Rat PINX1 Protein Mammalian Cell Rat His
PINX1-3177HCL Recombinant Human PINX1 293 Cell Lysate HEK293 Human Non
PINX1-4127R Recombinant Rat PINX1 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
PINX1-4127R-B Recombinant Rat PINX1 Protein Pre-coupled Magnetic Beads HEK293 Rat
Pinx1-4872M Recombinant Mouse Pinx1 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
PINX1-617H Recombinant Human PINX1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
PINX1-6750M Recombinant Mouse PINX1 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
PINX1-6750M-B Recombinant Mouse PINX1 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    PINX1 involved in several pathways and played different roles in them. We selected most pathways PINX1 participated on our site, such as Regulation of Telomerase, which may be useful for your reference. Also, other proteins which involved in the same pathway with PINX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Regulation of Telomerase DKC1,NR2F2,TNKS,SP3,MXD1,CMTM2A

    Protein Function

    PINX1 has several biochemical functions, for example, protein binding,telomerase RNA binding,telomerase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PINX1 itself. We selected most functions PINX1 had, and list some proteins which have the same functions with PINX1. You can find most of the proteins on our site.

    Function Related Protein
    telomerase RNA binding HNRNPC,WRAP53,TERT,DKC1,HNRNPU,NOP10,NHP2,GAR1
    protein binding BTG3,ALS2,PEX10,FIG4,SWSAP1,HOXB9,ABHD1,ADRB3,SPTBN1,AIMP1
    telomerase inhibitor activity MCRS1,POT1,POT1A

    Interacting Protein

    PINX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PINX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PINX1.

    TERF1;20475405;TERT;EIF1B;MRPS14;CUTA;SRP72;MT-CO2

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