PIK3C2G

  • Official Full Name

    phosphoinositide-3-kinase, class 2, gamma polypeptide

  • Overview

    The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The biological function of this gene has not yet been determined.

  • Synonyms

    PIK3C2G;phosphoinositide-3-kinase, class 2, gamma polypeptide;phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma;PI3K-C2-gamma;PTDINS-3-kinase C2 gamma;ptdIns-3-kinase C2 subunit gamma;phosphoinositide 3-kinase-C2-gamma;ph

Recombinant Proteins

  • Human
  • Mouse
  • Rat
  • E.coli
  • Sf9 Insect Cell
  • Insect Cell
  • Mammalian Cell
  • HEK293
  • His
  • GST
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
PIK3C2G-2672H Recombinant Human PIK3C2G protein, His-tagged E.coli Human His 11-336 aa
PIK3C2G-1453H Active Recombinant Human PIK3C2G, GST-tagged Sf9 Insect Cell Human GST 468-1203 aa
PIK3C2G-165H Active Recombinant Human PIK3C2G protein, GST-tagged Insect Cell Human GST 468-1203 a.a.
PIK3C2G-12799M Recombinant Mouse PIK3C2G Protein Mammalian Cell Mouse His
PIK3C2G-4459R Recombinant Rat PIK3C2G Protein Mammalian Cell Rat His
PIK3C2G-4119R Recombinant Rat PIK3C2G Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
PIK3C2G-4119R-B Recombinant Rat PIK3C2G Protein Pre-coupled Magnetic Beads HEK293 Rat
PIK3C2G-6735M Recombinant Mouse PIK3C2G Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
PIK3C2G-6735M-B Recombinant Mouse PIK3C2G Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    PIK3C2G involved in several pathways and played different roles in them. We selected most pathways PIK3C2G participated on our site, such as Inositol phosphate metabolism,Metabolic pathways,Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with PIK3C2G were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolic pathways UPRT,POLA1,ATP6V1F,PCCA,LASS1,PDXKB,ACSM2,MTHFR,UGT1A9,GMPPAA
    Phosphatidylinositol signaling system CALM,PTEN,PLCD1A,INPPL1,MTMR8,PIP4K2C,INPP5B,SYNJ1,IPPK,PIP5K2
    Inositol phosphate metabolism MIOX,INPP5D,PIP4K2A,MTMR14,INPPL1A,PIP4K2B,PIP5K1A,ITPKB,INPP5K,INPP4B

    Protein Function

    PIK3C2G has several biochemical functions, for example, 1-phosphatidylinositol-3-kinase activity,1-phosphatidylinositol-4-phosphate 3-kinase activity,ATP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PIK3C2G itself. We selected most functions PIK3C2G had, and list some proteins which have the same functions with PIK3C2G. You can find most of the proteins on our site.

    Function Related Protein
    1-phosphatidylinositol-3-kinase activity ATM,PIK3C2A,PIK3C2B,PIK3C3,PIK3CA,PIK3R3,PIK3CG,PIK3CD,PIK3CB
    1-phosphatidylinositol-4-phosphate 3-kinase activity PIK3C2A,PIK3CA,PIK3CG,PIK3CD,PIK3C2B,PIK3CB
    phosphatidylinositol phosphate kinase activity PIP5K2,PIP5K1BB,PIP5K1BA,PIP5K1AA,PIP5K1AB
    ATP binding DHX35,WNK2,ENTPD3,PRPF4B,MAP3K8,UCKL1,MAPK4,SCYL2,ACVR1L,KIFC1
    phosphatidylinositol binding SNX10B,SNX22,ITPR3,TNFAIP8L3,ING2,ARHGAP33,SNX17,SNX4,SNX32,SNX18B

    Interacting Protein

    PIK3C2G has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PIK3C2G here. Most of them are supplied by our site. Hope this information will be useful for your research of PIK3C2G.

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