PIGO
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Official Full Name
phosphatidylinositol glycan anchor biosynthesis, class O -
Overview
This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This protein is involved in the transfer of ethanolaminephosphate (EtNP) to the third mannose in GPI. At least three alternatively spliced transcripts encoding two distinct isoforms have been found for this gene. -
Synonyms
PIGO;phosphatidylinositol glycan anchor biosynthesis, class O;phosphatidylinositol glycan, class O;GPI ethanolamine phosphate transferase 3;DKFZp434M222;FLJ00135;MGC20536;MGC3079;FLJ00350;mFLJ00350;OTTHUMP00000021324;OTTHUMP00000021325;OTTMUSP00000007085;Phosphatidylinositol glycan anchor biosynthesis class O;Phosphatidylinositol glycan biosynthesis class O protein;Phosphatidylinositol glycan class O;PIG O;RP11-182N22.4;RP23-124L1.7;PIG-O;phosphatidylinositol-glycan biosynthesis class O protein
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PIGO-1708H | Recombinant Human PIGO, His-tagged | E.coli | Human | His | C-term-223aa |
Involved Pathway
PIGO involved in several pathways and played different roles in them. We selected most pathways PIGO participated on our site, such as Glycosylphosphatidylinositol(GPI)-anchor biosynthesis,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PIGO were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycosylphosphatidylinositol(GPI)-anchor biosynthesis | PIGS,PIGB,PIGYL,PIGN,PIGF,DPM2,PIGM,GPAA1,PIGV,PIGP |
| Metabolic pathways | TYRP1B,QDPRB2,CYP51,Atp5k,GALNT1,GALE,PDHA1A,H6PD,PNAT10,ACSS2L |
Protein Function
PIGO has several biochemical functions, for example, mannose-ethanolamine phosphotransferase activity,molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by PIGO itself. We selected most functions PIGO had, and list some proteins which have the same functions with PIGO. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| mannose-ethanolamine phosphotransferase activity | PIGN |
| molecular_function | MPPED1,TSPAN34,TMEM54,DNAAF3,TSNAXIP1,MUC6,CHTOPB,ACOT9.2,IGSF21A,TMEM106BA |
Interacting Protein
PIGO has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PIGO here. Most of them are supplied by our site. Hope this information will be useful for your research of PIGO.
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