PIGN
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Official Full Name
phosphatidylinositol glycan anchor biosynthesis, class N -
Overview
This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is expressed in the endoplasmic reticulum and transfers phosphoethanolamine (EtNP) to the first mannose of the GPI anchor. Two alternatively spliced variants, which encode an identical isoform, have been reported. -
Synonyms
PIGN;phosphatidylinositol glycan anchor biosynthesis, class N;phosphatidylinositol glycan, class N;GPI ethanolamine phosphate transferase 1;MDC4;PIG N;MCD4 homolog;phosphatidylinositol-glycan biosynthesis class N protein;MCD4;MCAHS;PIG-N;MCAHS1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PIGN-1707H | Recombinant Human PIGN, GST-tagged | E.coli | Human | GST | 26-334aa | |
| PIGN-6811Z | Recombinant Zebrafish PIGN | Mammalian Cells | Zebrafish | His |
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| PIGN-778H | Recombinant Human PIGN | Mammalian Cells | Human | His |
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| PIGN-3196HCL | Recombinant Human PIGN 293 Cell Lysate | HEK293 | Human | Non |
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| PIGN-3855H | Recombinant Human PIGN Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| PIGN-3855H-B | Recombinant Human PIGN Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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Involved Pathway
PIGN involved in several pathways and played different roles in them. We selected most pathways PIGN participated on our site, such as Glycosylphosphatidylinositol(GPI)-anchor biosynthesis,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PIGN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | B3GAT3,IVD,MIBP,NAT8L,CYP2P7,ALDH6A1,GCLC,PON3,PTDSS2,ALOX5 |
| Glycosylphosphatidylinositol(GPI)-anchor biosynthesis | PIGU,PIGYL,DPM2,GPAA1,PIGX,PIGV,PIGB,GPLD1,PIGO,PIGA |
Protein Function
PIGN has several biochemical functions, for example, mannose-ethanolamine phosphotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PIGN itself. We selected most functions PIGN had, and list some proteins which have the same functions with PIGN. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| mannose-ethanolamine phosphotransferase activity | PIGO |
Interacting Protein
PIGN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PIGN here. Most of them are supplied by our site. Hope this information will be useful for your research of PIGN.
FJX1;Unc93b1
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