PIGL
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Official Full Name
phosphatidylinositol glycan anchor biosynthesis, class L -
Overview
This gene encodes an enzyme that catalyzes the second step of glycosylphosphatidylinositol (GPI) biosynthesis, which is the de-N-acetylation of N-acetylglucosaminylphosphatidylinositol (GlcNAc-PI). Study of a similar rat enzyme suggests that this protein localizes to the endoplasmic reticulum. -
Synonyms
PIGL;phosphatidylinositol glycan anchor biosynthesis, class L;phosphatidylinositol glycan, class L;N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase;N acetylglucosaminylphosphatidylinositol deacetylase;Phosphatidylinositol glycan anchor biosynthesis class L;Phosphatidylinositol glycan class L;Phosphatidylinositol-glycan biosynthesis class L protein;PIG-L;PIGL_HUMAN;N-acetylglucosaminylphosphatidylinositol deacetylase
Recombinant Proteins
- Mouse
- Rat
- Zebrafish
- Human
- Bovine
- Mammalian Cell
- E.coli
- HEK293
- HEK293T
- E.coli expression system
- His
- His&Fc&Avi
- Myc&DDK
Involved Pathway
PIGL involved in several pathways and played different roles in them. We selected most pathways PIGL participated on our site, such as Glycosylphosphatidylinositol(GPI)-anchor biosynthesis,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PIGL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | TDO2,POLR2H,PDHA2,HIBADHB,NMNAT2,NMNAT1,POLR2F,ALDOC,PHOSPHO2,KCNG4 |
| Glycosylphosphatidylinositol(GPI)-anchor biosynthesis | PIGQ,PIGU,GPLD1,PIGF,PIGM,PIGV,PIGYL,PIGX,PIGO,PIGK |
Protein Function
PIGL has several biochemical functions, for example, N-acetylglucosaminylphosphatidylinositol deacetylase activity,hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PIGL itself. We selected most functions PIGL had, and list some proteins which have the same functions with PIGL. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| hydrolase activity | CES3A,CAPN3A,ADAMTS16,PGCP,REXO4,UGT1AB,KLK1B8,HYAL6,F9A,PTPREB |
Interacting Protein
PIGL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PIGL here. Most of them are supplied by our site. Hope this information will be useful for your research of PIGL.
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