PIGH
-
Official Full Name
phosphatidylinositol glycan anchor biosynthesis, class H -
Overview
This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. The protein encoded by this gene is a subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. -
Synonyms
PIGH;phosphatidylinositol glycan anchor biosynthesis, class H;phosphatidylinositol glycan, class H;phosphatidylinositol N-acetylglucosaminyltransferase subunit H;GPI H;GPIH;Phosphatidylinositol glycan anchor biosynthesis class H;Phosphatidylinositol glycan biosynthesis class H protein;Phosphatidylinositol glycan class H;Phosphatidylinositol N acetylglucosaminyltransferase subunit H;Phosphatidylinositol-glycan biosynthesis class H protein;PIG H;PIG-H;PIGH_HUMAN;OTTHUMP00000246879;phosphatidylinositol-glycan biosynthesis, class H protein;GPI-H
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PIGH-4460C | Recombinant Chicken PIGH | Mammalian Cell | Chicken | His |
|
|
| PIGH-686Z | Recombinant Zebrafish PIGH | Mammalian Cell | Zebrafish | His |
|
|
| PIGH-1351HCL | Recombinant Human PIGH cell lysate | Human | Non |
|
||
| PIGH-307H | Recombinant Human PIGH Protein, MYC/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
|
|
| Pigh-472M | Recombinant Mouse Pigh Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
|
Involved Pathway
PIGH involved in several pathways and played different roles in them. We selected most pathways PIGH participated on our site, such as Glycosylphosphatidylinositol(GPI)-anchor biosynthesis,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PIGH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | PDXKA,GALNTL2,PON1,WBSCR17,LIPCA,ST20-MTHFS,PGS1,MTHFD1,SPRA,MPST |
| Glycosylphosphatidylinositol(GPI)-anchor biosynthesis | PIGYL,PIGN,GPLD1,PIGS,PIGO,DPM2,PIGX,PIGP,PIGC,GPAA1 |
Protein Function
PIGH has several biochemical functions, for example, catalytic activity,phosphatidylinositol N-acetylglucosaminyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PIGH itself. We selected most functions PIGH had, and list some proteins which have the same functions with PIGH. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| catalytic activity | HOGA1,HSD17B6,SLC3A2,MDH1AA,APOBEC2B,ISOC2B,SLC3A2B,SPATA20,SLC27A1B,ALP3 |
Interacting Protein
PIGH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PIGH here. Most of them are supplied by our site. Hope this information will be useful for your research of PIGH.
sthA
Resources
Related Services
Related Products
References
- Nakamura, N; Inoue, N; et al. Expression cloning of PIG-L, a candidate N-acetylglucosaminylphosphatidylinositol deacetylase. JOURNAL OF BIOLOGICAL CHEMISTRY 272:15834-15840(1997).
- Karnan, S; Konishi, Y; et al. Simple Monitoring of Gene Targeting Efficiency in Human Somatic Cell Lines Using the PIGA Gene. PLOS ONE 7:-(2012).
