PHF6
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Official Full Name
PHD finger protein 6 -
Overview
This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate splicing results in multiple transcript variants, encoding different isoforms. -
Synonyms
PHF6;PHD finger protein 6;BFLS, BORJ, Borjeson Forssman Lehmann syndrome;CENP 31;centromere protein 31;KIAA1823;MGC14797;AC004383.6;BORJ;OTTHUMP00000024063;PHD like zinc finger protein;PHD-like zinc finger protein;BFLS;CENP-31
Recombinant Proteins
- Zebrafish
- Mouse
- Human
- Mammalian Cell
- E.coli
- HEK293
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PHF6-10154Z | Recombinant Zebrafish PHF6 | Mammalian Cell | Zebrafish | His |
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| PHF6-12731M | Recombinant Mouse PHF6 Protein | Mammalian Cell | Mouse | His |
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| PHF6-436H | Recombinant Human PHF6 Protein, His-tagged | E.coli | Human | His |
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| PHF6-3225HCL | Recombinant Human PHF6 293 Cell Lysate | HEK293 | Human | Non |
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| PHF6-6694M | Recombinant Mouse PHF6 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PHF6-6694M-B | Recombinant Mouse PHF6 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| PHF6-8432H | Recombinant Human PHF6 protein, His-tagged | E.coli | Human | His | 2-312aa |
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Involved Pathway
PHF6 involved in several pathways and played different roles in them. We selected most pathways PHF6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PHF6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
PHF6 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by PHF6 itself. We selected most functions PHF6 had, and list some proteins which have the same functions with PHF6. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
PHF6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PHF6 here. Most of them are supplied by our site. Hope this information will be useful for your research of PHF6.
LYAR;AXIN1;MYC;RPL10;ORC1;Prpf3;EDEM1
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