PHB2
-
Official Full Name
prohibitin 2 -
Overview
Prohibitin-2 is a protein that in humans is encoded by the PHB2 gene. -
Synonyms
PHB2;prohibitin 2;prohibitin-2;Bap37;BCAP37;p22;REA;D-prohibitin;B-cell associated protein;repressor of estrogen receptor activity;B-cell receptor-associated protein BAP37;BAP;PNAS-141;MGC117268
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Chicken
- Rat
- Schizosaccharomyces pombe
- S.cerevisiae
- E.coli
- Mammalian Cell
- HEK293
- E.coli expression system
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
PHB2 involved in several pathways and played different roles in them. We selected most pathways PHB2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PHB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PHB2 has several biochemical functions, for example, amide binding,estrogen receptor binding,protein C-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PHB2 itself. We selected most functions PHB2 had, and list some proteins which have the same functions with PHB2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| estrogen receptor binding | LEF1,FOXL2,XBP1,NKX3-1,DDX54,MED1,PRMT2,NCOA1,DDX5,STRN |
| protein N-terminus binding | RASSF1,MORF4L1,STX5A,EIF3E,HDAC1,DCTN4,GTF2H2,PEX5,ATM,CSNK2A2 |
| protein C-terminus binding | ATP1B1,CTBP1,MAPRE1,SNX17,ZBTB16,XRCC6,PEX10,TERF2,PEX16,KCNIP3 |
| protein binding | CLIC5,PSMD11,JRK,MAGEA11,NCOR2,DUSP23,SH3GLB1,C1orf105,C16orf70,FCHSD2 |
| amide binding | SRD5A2 |
Interacting Protein
PHB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PHB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PHB2.
ESR1;env;Tcr-alpha;4504555;PFAS;RIPK2;ABCB1;SLC3A2;EPB41;MYH8;JUP
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References
- Lacombe, J; Mange, A; et al. A Multiparametric Serum Marker Panel as a Complementary Test to Mammography for the Diagnosis of Node-Negative Early-Stage Breast Cancer and DCIS in Young Women. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 23:1834-1842(2014).
- Bavelloni, A; Piazzi, M; et al. Prohibitin 2 represents a novel nuclear AKT substrate during all-trans retinoic acid-induced differentiation of acute promyelocytic leukemia. FASEB JOURNAL 28:2009-2019(2014).
