PGLYRP3

  • Official Full Name

    peptidoglycan recognition protein 3
  • Overview

    This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This protein binds to murein peptidoglycans of Gram-positive bacteria.
  • Synonyms

    PGLYRP3;peptidoglycan recognition protein 3;peptidoglycan recognition protein I alpha precursor;PGLYRPIalpha;PGRP Ialpha;PGRPIA;PGRP-I-alpha;peptidoglycan recognition protein I alpha;peptidoglycan recognition protein I-alpha;peptidoglycan recogni

Recombinant Proteins

  • Mouse
  • Human
  • Mammalian Cell
  • HEK293
  • HEK293T
  • Mammalian cells
  • His
  • Non
  • His&Fc&Avi
  • Myc&DDK
  • Flag

    Involved Pathway

    PGLYRP3 involved in several pathways and played different roles in them. We selected most pathways PGLYRP3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PGLYRP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    PGLYRP3 has several biochemical functions, for example, N-acetylmuramoyl-L-alanine amidase activity,peptidoglycan binding,peptidoglycan receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PGLYRP3 itself. We selected most functions PGLYRP3 had, and list some proteins which have the same functions with PGLYRP3. You can find most of the proteins on our site.

    Function Related Protein
    zinc ion binding ZNF75D,ARIH1,DHX58,BRF2,ZFAND5,DYTN,KDM2B,RNF187,NEIL1,RNF180
    N-acetylmuramoyl-L-alanine amidase activity PGLYRP4,PGLYRP6,PGLYRP2,PGLYRP1,PGLYRP5
    peptidoglycan binding NOD1,TLR2,PGLYRP4,PGLYRP2,NLRP3,TREM2,PGLYRP1,RNASE7
    peptidoglycan receptor activity PGLYRP1,PGLYRP4,CD14,PGLYRP2

    Interacting Protein

    PGLYRP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PGLYRP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PGLYRP3.

    Resources

    References

    • Ginde, AA; Blatchford, PJ; et al. AGE-RELATED DIFFERENCES IN BIOMARKERS OF ACUTE INFLAMMATION DURING HOSPITALIZATION FOR SEPSIS. SHOCK 42:99-107(2014).
    • Maslinska, D; Laure-Kamionowska, M; et al. Toll-like receptors as an innate immunity bridge to neuroinflammation in medulloblastoma. FOLIA NEUROPATHOLOGICA 50:375-381(2012).

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