PGK2
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Official Full Name
phosphoglycerate kinase 2 -
Overview
This gene is intronless, arose via retrotransposition of the phosphoglycerate kinase 1 gene, and is expressed specifically in the testis. Initially assumed to be a pseudogene, the encoded protein is actually a functional phosphoglycerate kinase that catalyzes the reversible conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate, during the Embden-Meyerhof-Parnas pathway of glycolysis, in the later stages of spermatogenesis. -
Synonyms
PGK2;phosphoglycerate kinase 2;PGK 2;PGKPS;phosphoglycerate kinase, testis specific;phosphoglycerate kinase autosomal pseudogene;PGKB;dJ417L20.2
Recombinant Proteins
- Human
- Cynomolgus
- Rat
- E.coli
- Wheat Germ
- Mammalian Cell
- Insect Cell
- HEK293
- HEK293T
- GST
- Non
- His
- His&Fc&Avi
- Myc&DDK
Involved Pathway
PGK2 involved in several pathways and played different roles in them. We selected most pathways PGK2 participated on our site, such as Glycolysis / Gluconeogenesis,Metabolic pathways,Carbon metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PGK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Biosynthesis of amino acids | PKLR,GAPDH,ASL,PGAM1,PGAM1B,TPI1A,PRPS2,GPT2,GOT1,TKTL2 |
| Carbon metabolism | PHGDH,SUCLA2,PCXB,FBP2,PRPS1A,SDHA,MCEE,CPS1,CS,AMT |
| Glycolysis / Gluconeogenesis | ENO3,HKDC1,PKM2,FBP2,ALDOB,AKR1A1B,G6PC3,PCK1,ACSS2L,PKLR |
| Metabolic pathways | ENPP3,NDUFV1,CMPK2,ADSSL1,GRHPR,GALNT14,POLR3D,PIP5K1AA,NAT1,POLR2EB |
Protein Function
PGK2 has several biochemical functions, for example, ATP binding,phosphoglycerate kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PGK2 itself. We selected most functions PGK2 had, and list some proteins which have the same functions with PGK2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | ANKK1,CENPE,EPB42,DHX38,HSP90AA1.1,MAPK4,DDX59,STRADA,ACACA,IP6K2 |
| phosphoglycerate kinase activity | PGK1 |
Interacting Protein
PGK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PGK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PGK2.
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