PFKFB4
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Official Full Name
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 -
Synonyms
PFKFB4;6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4;6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4;PFK/FBPase 4;6PF-2-K/Fru-2,6-P2ase 4;6PF-2-K/Fru-2,6-P2ase testis-type isozyme;6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4
Recombinant Proteins
- Human
- Chicken
- Zebrafish
- Rat
- Cynomolgus
- Mouse
- Sf9 Insect Cell
- Mammalian Cell
- HEK293
- Mammalian cells
- HEK293T
- GST
- His
- Non
- Flag
- His&Fc&Avi
- Myc&DDK
Involved Pathway
PFKFB4 involved in several pathways and played different roles in them. We selected most pathways PFKFB4 participated on our site, such as Fructose and mannose metabolism,AMPK signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PFKFB4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fructose and mannose metabolism | FUK,TSTA3,AKR1B1L,HKDC1,TPI1,C12orf5,FPGT,ALDOC,ALDOB,Akr1b3 |
| AMPK signaling pathway | PFKFB3,PIK3CA,PRKAA1,CAB39L,TSC2,LEPR,Scd2,RAB8A,ELAVL1,CFTR |
Protein Function
PFKFB4 has several biochemical functions, for example, 6-phosphofructo-2-kinase activity,ATP binding,fructose-2,6-bisphosphate 2-phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PFKFB4 itself. We selected most functions PFKFB4 had, and list some proteins which have the same functions with PFKFB4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| fructose-2,6-bisphosphate 2-phosphatase activity | TIGARB,PFKFB2,C12orf5,TIGARA,PFKFB1,PFKFB3 |
| ATP binding | PRKCHA,AACS,MAPK9,CLK1,ABCA1,P2RX7,GRK1,ERCC6L2,STK3,UBE2R2 |
| 6-phosphofructo-2-kinase activity | PFKFB2,PFKFB4L,PFKFB3,PFKFB1,PFKFB2A |
Interacting Protein
PFKFB4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PFKFB4 here. Most of them are supplied by our site. Hope this information will be useful for your research of PFKFB4.
GADD45A;GSK3B;CSNK2B
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