PDSS1
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Official Full Name
prenyl (decaprenyl) diphosphate synthase, subunit 1 -
Overview
The protein encoded by this gene is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in this gene are a cause of coenzyme Q10 deficiency. -
Synonyms
PDSS1;prenyl (decaprenyl) diphosphate synthase, subunit 1;TPRT, trans prenyltransferase;decaprenyl-diphosphate synthase subunit 1;coenzyme Q1 homolog (yeast);COQ1;TPT;coenzyme Q1 homolog;trans-prenyltransferase 1;trans-prenyltransferase (TPT);p
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PDSS1-12599M | Recombinant Mouse PDSS1 Protein | Mammalian Cell | Mouse | His |
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| PDSS1-2423Z | Recombinant Zebrafish PDSS1 | Mammalian Cell | Zebrafish | His |
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| PDSS1-6617M | Recombinant Mouse PDSS1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PDSS1-6617M-B | Recombinant Mouse PDSS1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PDSS1 involved in several pathways and played different roles in them. We selected most pathways PDSS1 participated on our site, such as Terpenoid backbone biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDSS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Terpenoid backbone biosynthesis | NUS1,FNTA,MVD,HMGCS1,IDI2,HMGCR,MVDA,ACAT1,HMGCS2,GGPS1 |
Protein Function
PDSS1 has several biochemical functions, for example, metal ion binding,protein heterodimerization activity,contributes_to trans-hexaprenyltranstransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PDSS1 itself. We selected most functions PDSS1 had, and list some proteins which have the same functions with PDSS1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein heterodimerization activity | TLR6,GTF2A1,HIST1H2BP,SNX6,H3F3C,CD3G,BTBD11,NFKB1,SYCP2,KCNA3 |
| contributes_to trans-hexaprenyltranstransferase activity | PDSS2 |
| transferase activity | NME2A,UGT1A6A,ST3GAL5L,SMYD1B,FTSJD1,FUT9A,METTL23,CDYL,TKTB,FKRP |
| metal ion binding | EFCAB5,ZFP653,ARSI,FAHD2B,ZBED2,PDE9A,OVOL2,IREB2,AARSD1,ZFP598 |
Interacting Protein
PDSS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDSS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PDSS1.
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