PDLIM5
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Official Full Name
PDZ and LIM domain 5 -
Overview
The protein encoded by this gene is a LIM domain protein. LIM domains are cysteine-rich double zinc fingers composed of 50 to 60 amino acids that are involved in protein-protein interactions. LIM domain-containing proteins are scaffolds for the formation of multiprotein complexes. The proteins are involved in cytoskeleton organization, cell lineage specification, organ development, and oncogenesis. The encoded protein is also a member of the Enigma class of proteins, a family of proteins that possess a 100-amino acid PDZ domain in the N terminus and 1 to 3 LIM domains in the C terminus. Multiple transcript variants encoding different isoforms have been found for this gene, although not all of them have been fully characterized. -
Synonyms
PDLIM5;PDZ and LIM domain 5;PDZ and LIM domain protein 5;Enh;LIM;ENH1;Enigma homolog;Enigma like LIM domain protein;Enigma like PDZ and LIM domains protein;L 9;L9;OTTHUMP00000161598;OTTHUMP00000219307;OTTHUMP00000219309;OTTHUMP00000219310;OTTHUMP00000227958;enigma-like LIM domain protein;enigma-like PDZ and LIM domains protein
Recombinant Proteins
- Human
- Chicken
- Rat
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- Flag
- His&Fc&Avi
- Myc&DDK
Involved Pathway
PDLIM5 involved in several pathways and played different roles in them. We selected most pathways PDLIM5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PDLIM5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PDLIM5 has several biochemical functions, for example, actin binding,actinin binding,protein N-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDLIM5 itself. We selected most functions PDLIM5 had, and list some proteins which have the same functions with PDLIM5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein N-terminus binding | NBN,HDAC1,DCTN4,RELA,TDRD7,TBL1XR1,FEZ1,MORF4L1,NFE2,STXBP1 |
| actin binding | CAPZB,PXK,TWF1B,CXCR4,EZRA,WASF1,KLHL20,SPATA31,MSRB1,SNTB2 |
| protein binding | PABPC1,CASP8,TPRKB,NDE1,CBX7,DTL,PHF20L1,TWF2,TKT,R3HDM2 |
| protein kinase C binding | AVPR1B,SDC4,PRKCB,IRS1,TIRAP,SDPRA,PLEK,PKP2,AKT2,GNB2L1 |
| zinc ion binding | RNF41,ZNRF1,NR5A1,FTR54,LMO7,RNF181,NR3C2,IRGF4,SH3RF2,SLU7 |
| actinin binding | NFKB1,RELA,CSRP3,TTN,MICALL2,PKD2,PROM1 |
Interacting Protein
PDLIM5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDLIM5 here. Most of them are supplied by our site. Hope this information will be useful for your research of PDLIM5.
COIL;KRTAP10-7;ZYX;KRT40;CCDC136;GFI1B;q7cii8_yerpe;TRIM39;q9wmx2-pro_0000037548;npm_alk
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