PDCD11
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Official Full Name
programmed cell death 11 -
Overview
PDCD11 is a NF-kappa-B (NFKB1; 164011)-binding protein that colocalizes with U3 RNA (MIM 180710) in the nucleolus and;is required for rRNA maturation and generation of 18S rRNA (Sweet et al., 2003 (PubMed 14624448); Sweet et al., 2008;(PubMed 17654514)). -
Synonyms
PDCD11;programmed cell death 11;protein RRP5 homolog;ALG 4;KIAA0185;RRP5;apoptosis-linked gene 4;NF-kappa-B-binding protein;programmed cell death protein 11;ALG4;NFBP;ALG-4
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PDCD11-12531M | Recombinant Mouse PDCD11 Protein | Mammalian Cell | Mouse | His |
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| PDCD11-5520Z | Recombinant Zebrafish PDCD11 | Mammalian Cell | Zebrafish | His |
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| PDCD11-2422H | Recombinant Human PDCD11 protein, His-tagged | Yeast | Human | His | 1200-1420aa |
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| PDCD11-5344H | Recombinant Human PDCD11 protein, His&Myc-tagged | E.coli | Human | N-His&C-Myc | 1200-1420aa |
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| PDCD11-6572M | Recombinant Mouse PDCD11 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PDCD11-6572M-B | Recombinant Mouse PDCD11 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PDCD11 involved in several pathways and played different roles in them. We selected most pathways PDCD11 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PDCD11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
PDCD11 has several biochemical functions, for example, RNA binding,nucleic acid binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDCD11 itself. We selected most functions PDCD11 had, and list some proteins which have the same functions with PDCD11. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | RP9,SNRPB,RPL28,MRPS26,BST2,PNO1,DROSHA,NLRP11,CNOT1,HMGN2 |
| nucleic acid binding | EHD2,METTL4,ZFP458,DDX4,ZNF292A,JRKL,HNRPKL,NPM1B,ZEB2A,RNASE12 |
| transcription factor binding | RNF4,NFIA,TRIM11,PARK7,CAMTA2,MYOD1,FOXO4,HDAC3,TRERF1,JUNBA |
| RNA binding | SRP9,MOV10B.2,CELF6,HDLBPA,SETD1B,ILF3A,PPARGC1A,ALYREF,ZNF638,RBM14 |
Interacting Protein
PDCD11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDCD11 here. Most of them are supplied by our site. Hope this information will be useful for your research of PDCD11.
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References
- Ansell, SM; Lesokhin, AM; et al. PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's Lymphoma. NEW ENGLAND JOURNAL OF MEDICINE 372:311-319(2015).
- Chan, MMK; Kefford, RF; et al. Arthritis and Tenosynovitis Associated With the Anti-PD1 Antibody Pembrolizumab in Metastatic Melanoma. JOURNAL OF IMMUNOTHERAPY 38:37-39(2015).
