PCTK1
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Official Full Name
CDK16 cyclin-dependent kinase 16 -
Overview
The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. -
Synonyms
PCTK1;PCTAIRE;FLJ16665;PCTAIRE1;PCTGAIRE;cyclin-dependent kinase 16;OTTHUMP00000023208;OTTHUMP00000023209;OTTHUMP00000226801;OTTHUMP00000226803;PCTAIRE-motif protein kinase 1;cell division protein kinase 16;serine/threonine-protein kinase PCTAIRE-1
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Involved Pathway
PCTK1 involved in several pathways and played different roles in them. We selected most pathways PCTK1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PCTK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
PCTK1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by PCTK1 itself. We selected most functions PCTK1 had, and list some proteins which have the same functions with PCTK1. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
PCTK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PCTK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PCTK1.
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References
- Yanagi, T; Matsuzawa, S; et al. PCTAIRE1/PCTK1/CDK16: a new oncotarget?. CELL CYCLE 14:463-464(2015).
- Belotti, E; Polanowska, J; et al. The Human PDZome: A Gateway to PSD95-Disc Large-Zonula Occludens (PDZ)-mediated Functions. MOLECULAR & CELLULAR PROTEOMICS 12:2587-2603(2013).
