PCOLCE2
-
Official Full Name
procollagen C-endopeptidase enhancer 2 -
Overview
Procollagen C-endopeptidase enhancer 2 is an enzyme that in humans is encoded by the PCOLCE2 gene. -
Synonyms
PCOLCE2;procollagen C-endopeptidase enhancer 2;PCPE2;Procollagen C proteinase enhancer 2;Procollagen COOH terminal proteinase enhancer 2;2400001O18Rik;MGC187469;PCOLCE 2;PCOLE 2;PCPE 2;Procollagen C endopeptidase enhancer 2;Procollagen C-terminal proteinase enhancer protein 2;procollagen C-proteinase enhancer 2;procollagen COOH-terminal proteinase enhancer 2
Recombinant Proteins
- Human
- E.coli
- Mammalian Cell
- HEK293
- GST
- His&S
- HIS
- His
- Non
- His&SUMO
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PCOLCE2-1581H | Recombinant Human PCOLCE2, GST-tagged | E.coli | Human | GST | 1-276aa | |
| PCOLCE2-1110H | Recombinant Human PCOLCE2 protein, His & S-tagged | E.coli | Human | His&S | Cys154~Pro269 |
|
| PCOLCE2-150H | Recombinant Human PCOLCE2 Protein, HIS-tagged | E.coli | Human | HIS |
|
|
| PCOLCE2-826H | Recombinant Human PCOLCE2 | Mammalian Cell | Human | His |
|
|
| PCOLCE2-3374HCL | Recombinant Human PCOLCE2 293 Cell Lysate | HEK293 | Human | Non |
|
|
| PCOLCE2-3323H | Recombinant Human PCOLCE2 protein, His-SUMO-tagged | E.coli | Human | His&SUMO | 24-415aa |
|
| PCOLCE2-3807H | Recombinant Human PCOLCE2 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
|
|
| PCOLCE2-3807H-B | Recombinant Human PCOLCE2 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
|
||
| PCOLCE2-4186H | Recombinant Human PCOLCE2 Protein (Cys297-Cys415), N-His tagged | E.coli | Human | His | Cys297-Cys415 |
|
Involved Pathway
PCOLCE2 involved in several pathways and played different roles in them. We selected most pathways PCOLCE2 participated on our site, such as Collagen biosynthesis and modifying enzymes,Collagen formation,Extracellular matrix organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with PCOLCE2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Collagen biosynthesis and modifying enzymes | COL4A6,COL28A1,COL1A1,COL4A3,COL6A1,TLL1,ADAMTS3,BMP1,COL15A1B,COL16A1 |
| Extracellular matrix organization | FBN1,DST,COL9A1A,HAPLN1,CTSB,MFAP3,ITGB3A,EMID2,DDR1,MMP8 |
| Collagen formation | COL15A1B,MMP20,COL4A4,COL13A1,PRP,COL9A1B,COL9A1A,COL8A1,COL23A1,LEPRE1 |
Protein Function
PCOLCE2 has several biochemical functions, for example, collagen binding,heparin binding,peptidase activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PCOLCE2 itself. We selected most functions PCOLCE2 had, and list some proteins which have the same functions with PCOLCE2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| peptidase activator activity | APP,FN1,PSME4B,CLPX,FBLN1,CAV1,MMP14,PSME4,MMP25,PCOLCE |
| heparin binding | FGFRL1,CXCL11,GPNMB,FGFR1,CYR61L1,VEGFA,CTSG,GM4980,MMP7,SERPINE2 |
| collagen binding | VWF,MMP13,SERPINH1A,CD44,SMAD7,ABI3BP,LRRC15,DDR1,TLL1,NID2 |
Interacting Protein
PCOLCE2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PCOLCE2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PCOLCE2.
Resources
Related Services
Related Products
References
- Goldsmith, EC; Bradshaw, AD; et al. Cellular Mechanisms of Tissue Fibrosis. 2. Contributory pathways leading to myocardial fibrosis: moving beyond collagen expression. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 304:C393-C402(2013).
- Baicu, CF; Zhang, YH; et al. Effects of the absence of procollagen C-endopeptidase enhancer-2 on myocardial collagen accumulation in chronic pressure overload. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 303:H234-H240(2012).
